NFL 2021 Regular Season: Best Over & Under Picks for Week 1

NFL 2021 Regular Season: Best Over & Under Picks for Week 1

MyBookie has posted odds for NFL Week 1 over and under totals. As you might expect, there are plenty of intriguing matchups that could yield fantastic plays, including the first game of the new NFL Season between the defending Super Bowl Champion Tampa Bay Buccaneers and NFC East Division preseason favorite Dallas Cowboys. Check out totals for eight NFL Week 1 games, analysis, and early free picks so you can start planning your bets against their NFL odds

Best Over And Under Picks for Week 1 of the NFL

2021-2022 NFL Regular Season

  • When: Sep. 9, 2021 – Jan. 9, 2022

Dallas Cowboys at Tampa Bay Buccaneers

  • O 51 ½ (-110) / U 51 ½ (-110)

Even with Dak Prescott hurt for most of the season, the Dallas Cowboys averaged 24.7 points per. When Prescott was healthy, Dallas seemed to score at will. The Cowboys scored 40 against the Falcons in Week 2 and 38 against Cleveland in Week 4. But this season Tampa should field the best defense in football. Not only that, in Week 1 last year, the Boys scored 17 in a 17-20 loss to the Rams.  

NFL Over / Under Pick: Under  

Pittsburgh Steelers at Buffalo Bills

  • O 50 (-110) / U 50 (-110)

Last season, Buffalo ranked second in points per game. The Bills averaged 31.3. Pittsburgh averaged 26 points per. The Steelers’ defense was fantastic. It held opponents to 19 per. Buffalo beat Pittsburgh 26-15 in a Dec. 13, 2020 contest. A similar score could happen here because Buffalo’s defense should be better and Pittsburgh coach Mike Tomlin gets the best out of every player on defense. 

NFL Over / Under Pick: Under 

Arizona Cardinals at Tennessee Titans

  • O 51 ½ (-110) / U 51 ½ (-110)

This one goes over by a mile. Neither team has a great defense. More importantly, both squads are loaded on offense. Cardinal quarterback Kyler Murray should take the next step to greatness. Ryan Tannehill can now throw the ball to A.J. Brown and Julio Jones. If Tannehill wants to hand the ball off, he can do so to the best running back in the NFL, Derrick Henry. 

NFL Over / Under Pick: Over 

Philadelphia Eagles at Atlanta Falcons

  • O 48 (-110) / U 48 (-110)

On paper, here’s another game that should blast through the over. New Atlanta Falcons head coach Arthur Smith called plays for the Tennessee Titans last season. The Titans averaged 30.7 points per. If the Eagles start Jalen Hurts, which they should, Philadelphia should average over 24 per. Hurts has that kind of talent. Both defenses will be horrendous just like in 2020.

NFL Over / Under Pick: Over  

San Francisco 49ers at Detroit Lions

  • O 46 (-110) / U 46 (-110)

Detroit could field the worst defense and one of the worst offenses in the league. Lions’ quarterback Jared Goff can start in the NFL. But Goff is hesitant. He doesn’t make decisions fast enough. San Francisco’s offense will be better with a healthy Jimmy Garoppolo. It shouldn’t be good enough for this to go over.  

NFL Over / Under Pick: Under 

Cleveland Browns at Kansas City Chiefs

  • O 52 ½ (-110) / U 52 ½ (-110)

This could be a scoring fest classic, but it likely won’t. The Browns averaged 148.4 rushing yards per game last season. Cleveland is a run first squad who only unleashes Baker Mayfield when they get down by more than 14 points. That probably happen here because Patrick Mahomes has become a master at taking his time before scoring a TD. Don’t be surprised if one of these teams wins a 24-21 type game. 

NFL Over / Under Pick: Under  

Miami Dolphins at New England Patriots

  • O 45 (-110) / U 45 (-110)

The Dolphins won’t force the issue. The Patriots may start rookie Mac Jones. That will be their best chance of winning this season. Even if they start Cam Newton, coach Bill Belichick will have the same process, hand the ball off, eat up clock with short passes, and then lean on a revamped defense. This goes under.  

NFL Over / Under Pick: Under

Chicago Bears at Los Angeles Rams

  • O 45 (-110) / U 45 (-110)

The Los Angeles Rams should have a much stronger offense in 2020 than they had in 2021. But the real reason to like over in this game is because Andy Dalton gives Chicago coach Matt Nagy a veteran quarterback who can throw the rock. Dalton has skills, which means Chicago should average at least 23 to 27 points each game. The Rams should average close to 30. Last season, the Rams had a great defense. This season, LAR must play without 2020 starting safety John Johnson and starting cornerback Troy Hill. Also, depth on the defense could be an issue.  

NFL Over / Under Pick: Over  

 
 

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