We’ve had our first head coach firing of the new season and to no surprise it was the winless Washington Redskins dumping Jay Gruden. Bill Callahan takes over for the rest of this season, which is already lost. Here’s a look at each Week 6 game alongside the latest pro-football odds and our ATS pick.
2019 NFL Week 6 Odds, Overview & Predictions for Each Game
NY Giants at New England
- NFL Week 6 Odds: Patriots -17.5
The Thursday night game and also the biggest spread on the board by far. New York will be without receiver Sterling Shepard for a while as he’s dealing with his second concussion of the season already. The team might get back top running back Saquon Barkley this week though.
Week 6 Pick: Giants.
Carolina vs. Tampa Bay
- NFL Week 6 Odds: Buccaneers +2
The Bucs are the home team for this 9:30 AM ET start in London. Carolina lost at home to the Bucs in Week 2 and that was the last game that starting Panthers QB Cam Newton played. He’s not expected to be ready this week, either.
Week 6 Pick: Panthers.
Cincinnati at Baltimore
- NFL Week 6 Odds: Ravens -12
The Bengals are one of the NFL’s winless teams. Coach Zac Taylor confirmed A.J. Green (ankle) won’t practice this week and will be inactive vs. the Ravens. Green hasn’t yet played this season. Meanwhile, Ravens coach John Harbaugh said Monday that Marquise Brown’s ankle injury is “nothing serious.” Harbaugh added that the Ravens don’t believe Hollywood is dealing with a long-term issue. Brown caught 3-of-5 targets for 22 yards and a touchdown in Week 5 against the Steelers.
Week 6 Pick: Ravens.
Seattle at Cleveland
- NFL Week 6 Odds: Browns -2
This line could change depending on what the Browns did Monday vs. San Francisco and if any key players were injured. Seattle is on extra rest after edging the Rams by a point last Thursday. Russell Wilson completed 17-of-23 passes for 268 yards and four touchdowns for a perfect rating.
Week 6 Pick: Browns.
Houston at Kansas City
- NFL Week 6 Odds: Chiefs -5
First-ever pro meeting between stellar young quarterbacks Deshaun Watson of Houston and Patrick Mahomes of Kansas City. It’s possible the Chiefs will see the return of Pro Bowl receiver Tyreek Hill this week from injury.
Week 6 Pick: Chiefs.
New Orleans at Jacksonville
- NFL Week 6 Odds: Jaguars -1.5
The Saints are unbeaten since Drew Brees went down with a thumb injury. He won’t play this week, either. Teddy Bridgewater completed 26-of-34 passes for 314 yards, four touchdowns and an interception in the Saints’ 31-24, Week 5 win over the Bucs. The Jags lost at Carolina.
Week 6 Pick: Saints.
Philadelphia at Minnesota
- NFL Week 6 Odds: Vikings -3
The Vikings pounded the Giants on Sunday behind big games from Kirk Cousins and Dalvin Cook. Meanwhile, Philly easily handled the Jets. Coach Doug Pederson said DeSean Jackson (abdomen) is still rehabbing but “getting close” to returning.
Week 6 Pick: Vikings.
Washington at Miami
- NFL Week 6 Odds: Dolphins +3.5
The worst matchup of the decade? Even though the Redskins are hot trash, they aren’t ready to turn the team over to rookie QB Dwayne Haskins yet.
The Redskins have stressed the need to be patient with Haskins, the 15th overall selection in April’s draft. Miami comes off its bye week.
Week 6 Pick: Dolphins.
San Francisco at LA Rams
- NFL Week 6 Odds: Rams -4
Line could change depending on what happened in the Niners’ game on Monday vs. Cleveland. The Rams are off a loss last Thursday to Seattle. Rams linebacker Clay Matthews is expected to miss four weeks with a broken jaw. WR Brandin Cooks is in the concussion protocol.
Week 6 Pick: Rams.
Atlanta at Arizona
- NFL Week 6 Odds: Cardinals +2
Has there been a more disappointing team this year than the one-win Falcons? Arizona got the first win of the Kyler Murray/Kliff Kingsbury era on Sunday in Cincinnati. Kingsbury said David Johnson (back) will be monitored all week. Seems likely that Johnson plays.
Week 6 Pick: Falcons.
Dallas at NY Jets
- NFL Week 6 Odds: Jets +8.5
Will New York get Sam Darnold back from mono this week? He came close to play in Sunday’s loss to Philly but ultimately wasn’t cleared. Probably will know by Wednesday if Darnold plays. Dallas, meanwhile, has dropped back-to-back games.
Week 6 Pick: Jets if Darnold plays.
Tennessee at Denver
- NFL Week 6 Odds: Broncos -2.5
The Titans will have a new kicker for this one. In Sunday’s loss to Buffalo, Cairo Santos missed a 50-yard field goal in the second quarter as well as a 36-yard attempt with 49 seconds left in the first half. The Bills blocked a 33-yard field goal attempt in the fourth quarter and Santos later missed a 53-yarder. He was cut Monday. Denver got its first win for new coach Vic Fangio, upsetting the Chargers.
Week 6 Pick: Broncos.
Pittsburgh at LA Chargers
- NFL Week 6 Odds: Chargers -6.5
Pittsburgh will be turning to undrafted rookie Devlin Hodges this week almost surely. It would be his first NFL start. Hodges finished out Week 5 at QB, nearly leading the Steelers to an upset win over Baltimore after Mason Rudolph exited with a concussion on a hit that knocked him unconscious.
Week 6 Pick: Chargers.
Detroit at Green Bay
- NFL Week 6 Odds: Packers -4.5
Monday nightery. The Lions are off their bye week and have won the past four in this series. Not clear if the Packers will have top receiver Davante Adams after he missed Sunday’s win in Dallas due to injury. Also not yet clear if running back Jamaal Williams will play after missing Week 5 with a concussion.
Week 6 Pick: Packers.
More NFL Week 6 Betting News
- 49ers vs Rams 2019 NFL Week 6 Spread & Betting Analysis
- Steelers vs Chargers 2019 NFL Week 6 Odds & Pick for Sunday Night
- Titans vs Broncos 2019 NFL Week 6 Lines, Game Info & Prediction
- NFL Picks Week Six (Ep. 736)
- Cowboys vs Jets 2019 NFL Week 6 Betting Lines & Expert Analysis
- Falcons vs Cardinals 2019 NFL Week 6 Odds & Game Preview
- Texans vs Chiefs 2019 NFL Week 6 Odds, Preview & Prediction
- Saints vs Jaguars 2019 NFL Week 6 Odds, Preview & Pick
- Redskins vs Dolphins 2019 NFL Week 6 Spread & Betting Analysis
- Eagles vs Vikings 2019 NFL Week 6 Lines, Game Analysis & Prediction
- Seahawks vs Browns 2019 NFL Week 6 Odds, Preview & Pick
- Panthers vs Buccaneers 2019 NFL Week 6 Odds & Expert Pick
- 2019 NFL Week 6 Parlay Betting Picks
- Bengals vs Ravens 2019 NFL Week 6 Lines & Game Prediction