San Francisco 49ers Top 2016 Regular Season NFL Odds

If you’re ready for some online NFL lines and expert picks then you’ve certainly come to the right place! Thanks to the release of odds on nearly every game on the 2016 NFL regular season schedule, you can start making plans to cash in right now in the mybookie.ag sportsbook! Now, let’s get started with my four expert picks on a quartet of San Francisco 49ers 2016 regular season games.

Online NFL Lines and Expert Picks Reveal San Francisco 49ers Top NFL Odds for 2016 Regular Season!

Week 1

Los Angeles Rams (-2) at San Francisco

Analysis: I have no idea why the Rams are favored over the Niners despite being on the road in this longtime NFC West divisional battle, but I’m not buying it! These two teams split last year’s two regular season meetings wit both winning and covering the NFL betting line at home. I’m going to rake the new-look Niners and Chip Kelly explosive offensive style, to simply outscore Jeff Fisher’s Rams in this one. The Pick: San Francisco 28 Los Angeles 24

Week 6

San Francisco at Buffalo Bills (-7)

Analysis: The Niners may not be quite as good as the Buffalo Bills in 2016, but they won’t be as far off if you ask me. Buffalo has talent on both sides of the ball, but they’re also led by a head coach in Rex Ryan whose mouth can’t match his bravado or skill. I’m going with the Niners to at least cover the spread at home in this Week 6 showdown. The Pick: Buffalo 27 San Francisco 24

Week 7

Tampa Bay Buccaneers at San Francisco (PK)

Analysis: The Niners and Bucs haven’t met since 2013 and have played just 10 times since 1994, so I don’t think history will matter much in this Week 7 pairing, although you should know that the Bucs have lost four of the last five meetings. I think a better indication of how Tampa Bay will perform in this contest is to look at the fact that they lost their final three road games last season while failing to cover the NFL betting odds each time out. San Francisco is at home in this one with Kelly going up against first-time head coach Dirk Koetter. The Niners win outright. The Pick: San Francisco 31 Tampa Bay 28

Week 13

San Francisco at Chicago Bears (-5)

Analysis: While I really like Bears head coach John Fox, I certainly don’t feel the same way about enigmatic quarterback Jay Cutler. More importantly, Chicago lost its final five home games a year ago while failing to cover the spread in three straight and four of five. I like the Bears to get the home win in this late-season matchup, but not by a touchdown. I like Chip Kelly’s offensive genius to find a way to keep the final score close. My final NFL lines and expert picks prediction says the Niners lose by a field goal. The Pick: Chicago 24 San Francisco 21