A pair of NFC teams will get together at Levi’s Stadium in Santa Clara, California on Sunday. This is part of the Week 11 slate in the NFL. The San Francisco 49ers won the last meeting between these two teams, which came in December of 2022. The 49ers beat the Buccaneers 35-7 in that game.
Tampa Bay comes into the game with a 4-5 record, which is second place in the NFC South. The Buccaneers are chasing New Orleans, who is 5-5. Tampa Bay is coming off a home win on Sunday over the Tennessee Titans.
For the San Francisco 49ers, they are also coming off a win. Following their bye, the 49ers smacked the Jacksonville Jaguars in Florida on Sunday. The 49ers are now 6-3, and tied with the Seahawks for the top spot in the NFC West.
The San Francisco 49ers are favorites in this game. The 49ers are big favorites, as they are listed at -11.5 over the Buccaneers. The total for this game is listed at 41.5. If you like the Buccaneers as the upset winner, you can grab them at +430 on the moneyline.
MyBookie offers the NFL lines, game analysis, and betting pick for Tampa Bay Buccaneers versus the San Francisco 49ers which are playing on Week 11 of the NFL season.
Buccaneers vs 49ers Odds and Betting Prediction for this Week 11 Matchup | MyBookie NFL Week 11 Regular Season Preview
Tampa Bay Buccaneers vs San Francisco 49ers | NFL Week 11
ATS: 49ers -11.5
Money line: Buccaneers +450 / 49ers -650
Over/Under: 41.5
Sunday, November 19th, 2023 at 4:05 pm ET | FOX
Levi’s Stadium, Santa Clara, CA
Can the 49ers Win this Game? | 49ers Getting Back on Track
The San Francisco 49ers won their first five games, and were the talk of the town. In each of those five games, the 49ers scored 30+ points. Then, San Francisco went through a stretch where they scored 17 in three straight games, and lost them all to the Browns, Vikings and Cincinnati. The 49ers got back on track against the Jaguars.
Christian McCaffrey went the first 8 games of the season, scoring a touchdown in each of those games. McCaffrey did not score on Sunday, and the streak was snapped. Despite that, the running back needs 253 yards to reach 1,000 on the season, and he has 9 touchdowns.
McCaffrey is also one of the top receivers for the 49ers. He is third behind Brandon Aiyuk and George Kittle. Aiyuk leads with 675 yards, while Kittle and McCaffrey are tied with four touchdown receptions. Deebo Samuel has been in and out of the lineup, but is fourth.
All of that, and no talk about Brock Purdy. Purdy has started every game for the 49ers, and has 15 passing touchdowns, and 5 interceptions, and has been sacked 16 times on the season. The 49ers have used backup Sam Darnold to throw three passes this season.
Defense Got Better
As if the 49ers defense was not scary enough. Over the trade deadline, the defense got better. The 49ers added former Washington Commanders star Chase Young to the roster. Young now joins the likes of Nick Bosa, Fred Warner and Dre Greenlaw. The 49ers have a total of 23 sacks, with Bosa and Javon Hargrave leading the way with 4.5. The defense has been able to turn opponents over 19 times this season, with 13 interceptions. But, the 49ers have yet to score a defensive touchdown in 2023.
Can the Buccaneers Win this Game? | Buccaneers Glad to be Back to Winning
The win for the Tampa Bay Buccaneers was much needed. Tampa Bay had dropped four straight following the 3-1 start. During those four games, the Buccaneers lost three of them by a single score or less. Tampa Bay on the season is scoring 19.8 points per game, which is 22nd in the league. Defensively, they are allowing just 19.2 per game.
Baker Mayfield has kept Tampa Bay in most games this season. The signal caller has over 2,100 passing yards and 14 touchdowns. Veteran Mike Evans is 263 yards away from 1,000 on the season, and has six touchdown receptions. Rachaad White is the top running back for Tampa Bay, with 429 yards and three touchdowns.
Defense Wins Championships
The Tampa Bay defense on the season has forced 9 fumbles, and caused 8 interceptions. Antonie Winfield Jr is the man responsible for three of the forced fumbles, while Shaq Barrett has two. Dee Delaney and Christian Izien lead the team with two interceptions. Barrett’s lone interception was returned for a touchdown for the Buccaneers.
Vita Vea and Shaq Barrett are getting after the quarterback, and have a combined 8.5 sacks on the season. The Buccaneers have not allowed more than 17 in any of their four wins this season.
Next Up
The 49ers have back to back games at the 49ers and Eagles, before hosting the Seahawks next on their schedule. For Tampa Bay, they are starting back to back road games. Next, they are in Indianapolis. Following that, the Buccaneers will host the Panthers on December 3rd, before going back on the road to Atlanta and Green Bay.
Buccaneers vs 49ers Final Betting Analysis | 49ers Smash Buccaneers
Stop the count! Not a fair fight! The 49ers got rest, they got healthy and they got better. The 49ers are going to be a tough team to slow down as the second half of the season moves along. San Francisco can do it on both sides of the ball.
The quarterback play was up and down, but Purdy has shown he can play when it matters. The 49ers have the best running back in the league, and their defense is as scary as any defense in the league. San Francisco is at home here, and it’s going to be a blowout. Take the 49ers -11.5 over the Buccaneers.
The final score prediction for this game is the San Francisco 49ers 38-10 over the Tampa Bay Buccaneers in Week 11 of the National Football League. We hope you enjoy this game between these two NFC teams. We are looking forward to this game, and all the action in the National Football League for Week 11. Best of luck!
NFL Week 11 Pick: San Francisco 49ers -7 / Over 40 | Bet Buccaneers vs 49ers
MyBookie Betting Lines for the Game
Tampa Bay Buccaneers Last 5
| Date | OPP | Result |
|---|---|---|
| 11/12/23 | vs TEN | W20-6 |
| 11/5/23 | @ HOU | L39-37 |
| 10/26/23 | @ BUF | L24-18 |
| 10/22/23 | vs ATL | L16-13 |
| 10/15/23 | vs DET | L20-6 |
Tampa Bay Buccaneers Injury Report
| Name | Position | Status | DATE |
|---|---|---|
| Ryan Neal S | Questionable | Nov 15 |
| Devin White LB | Questionable | Nov 15 |
| Luke Goedeke OT | Questionable | Nov 15 |
| Mike Evans WR | Questionable | Nov 15 |
| Josh Hayes S | Questionable | Nov 14 |
NFC South Standings | Tampa Bay Buccaneers
| Team | W | L | PCT | Strk |
|---|---|---|---|---|
| New Orleans Saints | 5 | 5 | .500 | L1 |
| Tampa Bay Buccaneers | 4 | 5 | .444 | W2 |
| Atlanta Falcons | 4 | 6 | .400 | W2 |
| Carolina Panthers | 1 | 8 | .111 | L2 |
San Francisco 49ers Last 5
| Date | OPP | Result |
|---|---|---|
| 11/12/23 | @ JAX | W34-3 |
| 10/29/23 | vs CIN | L31-17 |
| 10/23/23 | @ MIN | L22-17 |
| 10/15/23 | @ CLE | L19-17 |
| 10/8/23 | vs DAL | W42-10 |
San Francisco 49ers Injury Report
| Name | Position | Status | DATE |
|---|---|---|
| Nick Zakelj OT | IR | Nov 15 |
| Demetrius Flannigan-Fowles LB | Questionable | Nov 14 |
| Anton Harrison OT | Questionable | Nov 14 |
| Colton McKivitz OT | Questionable | Nov 13 |
| – |
NFC South Standings | San Francisco 49ers
| Team | W | L | PCT | Strk |
|---|---|---|---|---|
| San Francisco 49ers | 6 | 3 | .667 | W1 |
| Seattle Seahawks | 6 | 3 | .667 | W1 |
| Los Angeles Rams | 3 | 6 | .333 | L3 |
| Arizona Cardinals | 2 | 8 | .200 | W1 |
Tampa Bay Buccaneers vs San Francisco 49ers Betting Trends
- San Francisco is 5-4-0 against the spread this year.
- The 49ers have been favored by 12 points or more once this season, and covered the spread.
- San Francisco games this year have gone over the total in four out of nine opportunities (44.4%).
- When playing as moneyline favorites, the 49ers have won 66.7% of the time (6-3).
- San Francisco has played as a moneyline favorite of -600 or shorter in only one game this season, which it won.
- Based on this matchup’s moneyline, the 49ers’ implied win probability is 85.7%.
- Tampa Bay is 6-3-0 against the spread this season.
- This season, Tampa Bay games have hit the over twice.
- This season, the Buccaneers have been the underdog six times and won two of those games.
- Tampa Bay has not entered a game this season with longer moneyline odds than +440.
- Oddsmakers have implied with the moneyline set for this matchup that the Buccaneers have a 18.5% chance to win.
The following NFL betting odds are based on MyBookie Sportsbook.
Super Bowl Odds to Win this 2025 NFL Season
| Teams | Odds |
|---|---|
| San Francisco 49ers | +550 |
| Kansas City Chiefs | +700 |
| Baltimore Ravens | +800 |
| Buffalo Bills | +1000 |
| Detroit Lions+1200 | |
| Cincinnati Bengals | +1300 |
| Dallas Cowboys | +1600 |
| Philadelphia Eagles | +1800 |
| Miami Dolphins | +2000 |
| Green Bay Packers | +2200 |
| Houston Texans | +2200 |
| LA Chargers | +2500 |
| New York Jets | +2500 |
| Jacksonville Jaguars | +3500 |
| Los Angeles Rams | +3500 |
| Cleveland Browns | +4000 |
| Minnesota Vikings | +4000 |
| Atlanta Falcons | +5000 |
| Chicago Bears | +5000 |
| Indianapolis Colts | +5000 |
| Denver Broncos | +7500 |
| Las Vegas Raiders | +7500 |
| New Orleans Saints | +7500 |
| Pittsburgh Steelers | +7500 |
| Seattle Seahawks | +7500 |
| Tampa Bay Buccaneers | +7500 |
| Arizona Cardinals | +10000 |
| New England Patriots | +15000 |
| New York Giants | +15000 |
| Tennessee Titans | +15000 |
| Washington Commanders | +15000 |
| Carolina Panthers | +25000 |
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