Cardinals vs. Bills: Week 10 Line and Betting Trends

Written by on November 10, 2020

The Buffalo Bills (7-2) will battle to keep their three-game winning streak intact as they are 2.0-point underdogs against the Arizona Cardinals (5-3) on Sunday, November 15, 2020 at State Farm Stadium. The game’s point total is set at 55.5.

Game Info

  • Game Day: Sunday, November 15, 2020
  • Game Time: 4:05 PM ET
  • TV Channel: CBS
  • Location: Glendale, AZ
  • Stadium: State Farm Stadium
Click here to place a bet on the Cardinals or the Bills in their matchup on 11/15/2020.

Betting Information

Cardinals vs Bills Betting Information
Favorite Spread Favorite Spread Odds Underdog Spread Odds Total Over Total Odds Under Total Odds Favorite Moneyline Underdog Moneyline
Cardinals -2.0 -110 -110 55.5 -110 -110 -130 110

Cardinals Betting Insights

  • Just five of Arizona’s eight games this year have gone over the point total (25% of its opportunities).
  • Arizona has compiled a 5-3 record against the spread this season.
  • The Cardinals are just 2-3 ATS when playing as at least 2.0-point favorites.
  • The Cardinals, on average, score 3.3 more points per game this season (29.2) than the Bills allow (25.9).
  • When they meet or go over their scoring average this season, Arizona is 4-1 and 4-1 against the spread.
  • When the Buffalo defense allows 25.9 points or fewer this year, the Bills have pieced together a 4-0 overall record and a 2-2 record against the spread.
Click here to bet on the Cardinals to win the Super Bowl

Bills Betting Insights

  • Buffalo’s games have hit the over in seven out of nine outings this season (77.8%).
  • Buffalo has compiled a losing 4-5 record against the spread this season.
  • The Bills have a losing ATS record of 2-4 when playing as at least 2.0-point underdogs.
  • The Bills, on average, score 4.4 more points per game this season (26.9) than the Cardinals allow (22.5).
  • Buffalo is 5-0 overall and 4-1 against the spread when they score at least 26.9 points this season.
  • Arizona is 4-0 overall and 4-0 against the spread this season in games where they allow fewer than 22.5 points.
Click here to bet on the Bills to win the Super Bowl

Computer Picks

Computer picks for Cardinals vs Bills
ATS Over/Under Score Prediction
Bills (+2) Under (55.5) Cardinals 27 Bills 25

Total Facts

  • The Cardinals’ average point total in matchups this year is 51.8, 3.7 points less than the total in this game.
  • The average total for Bills games this year is 2.7 fewer points than the point total of 55.5 in this outing.
  • The Cardinals and their opponents have combined to record more than 55.5 points in 25% of their games this season (two of eight opportunities).
  • The Bills have played in four games this year (out of nine total matchups — 44.4% of opportunities) where they combined with their opponents to score at least 55.5 points.
  • The Cardinals and the Bills combine to average 0.6 more points per game than the total of 55.5 set for this game.
  • The Cardinals and the Bills have seen their opponents average a combined 7.1 fewer points per game than the point total of 55.5 set in this game.
Click here to bet on LIVE NFL Games

Cardinals vs Bills: Last 5 Meetings

Buffalo has an edge against Arizona in the past five meetings between these two squads, collecting a 4-1 record in those games. Buffalo outscored Arizona 138-110 in those five head-to-head matchups.

Cardinals vs Bills: Last Five Meetings
Date Home Team Total Yards Result
9/25/2016 Bills 348-297 ARI 33-18 BUF
10/14/2012 Cardinals 332-306 ARI 19-16 BUF
10/5/2008 Cardinals 41-17 ARI
10/31/2004 Bills 38-14 BUF
12/19/1999 Cardinals 31-21 BUF

Betting Insights: Last Three Games (Both Teams)

  • Arizona is 2-1 against the spread and 2-1 straight up over their last three contests.
  • The over has been familiar to Arizona. They have gone over the total two times in their last three outcomes.
  • The Cardinals and their opponents have combined to score an average of 61.3 points over their last three games, 5.8 more than the 55.5 over/under in this matchup.
  • Buffalo has struggled to cover, going 1-2 against the spread and 3-0 straight up in their last three outcomes.
  • Buffalo has hit the over two times in their last three outcomes.
  • The Bills total over the last three games is 5.2 points fewer than the 55.5 total listed for this matchup.

Injury Report

Cardinals: OLB Chandler Jones: Out (Biceps), CB Dre Kirkpatrick: Questionable (Thigh), G J.R. Sweezy: Out (Elbow), CB Robert Alford: Out (Torn Pectoral), OLB Devon Kennard: Out (Illness), RB Kenyan Drake: Questionable (Ankle), CB Kevin Peterson: Questionable (Concussion), OLB Isaiah Irving: Out (Back), DE Zach Allen: Out (Ankle), CB Byron Murphy Jr.: Out (Illness), DT Rashard Lawrence: Out (Calf)

Bills: RB Taiwan Jones: Questionable (Hamstring), CB Josh Norman: Questionable (Hamstring), RB T.J. Yeldon: Questionable (Back), C Mitch Morse: Questionable (Concussion), CB Tre’Davious White: Questionable (Ankle), OLB Matt Milano: Out (Pectoral), OT Cody Ford: Questionable (Ankle), TE Tommy Sweeney: Out (Illness), CB Cam Lewis: Out (Wrist), OLB Tyrel Dodson: Out (Hamstring), WR Isaiah Hodgins: Out (Shoulder)


More Recent NFL News