San Francisco 49ers 2021 NFL Calendar Betting Predictions

San Francisco 49ers 2021 NFL Calendar Betting Predictions

Written by on May 26, 2021

The San Francisco 49ers are one of the hottest squads in NFL futures. Most feel the Niners have a shot to not only beat the Los Angeles Rams and win the NFC West, but to also win the NFC and the Super Bowl. Check out an analysis of San Fran’s schedule and their Super Bowl 56 odds so you can plan your bets against their NFL odds.  

NFL Betting – San Francisco 49ers Calendar Odds & Analysis For the 2021-22 Season

2021 NFL Season: Why Are the Niners a Favorite to Win the Super Bowl?

  • When: Sep. 9 – Jan. 9

San Francisco 49ers Schedule & Odds Analysis

  • Odds to win Super Bowl 56: +1200

What is the San Francisco 49ers strength of schedule?

San Francisco’s strength of schedule is nineteenth. The Niners must play their top NFC West foes twice this season. 

The Arizona Cardinals, the Los Angeles Rams, and the Seattle Seahawks all have playoff aspirations. Some, like the Rams, believe they can win the Super Bowl.

Outside of the 6 games versus their NFC West opponents, San Francisco’s schedule doesn’t appear overly difficult. The NFC West battles the NFC North, which means SF takes on the Green Bay Packers, Chicago Bears, Detroit Lions, and Minnesota Vikings.

All four are winnable games. The NFC West also takes on the AFC South. The Houston Texans, Jacksonville Jaguars, Tennessee Titans, and the Indianapolis Colts are the teams in the AFC South. Again, all winnable contests.

The 49ers also play the Cincinnati Bengals, Atlanta Falcons, and Philadelphia Eagles.  

What are some of the key games on the Niners’ schedule?

The Niners could run the table against non-division foes. So the real question is how well San Francisco will play against the Seahawks, Rams, and Cardinals. Check out dates for those key 6 games.

  • Oct. 3 vs. Seattle
  • Oct. 10 at Arizona
  • Nov. 7 vs. Arizona
  • Nov. 14 vs. Los Angeles Rams
  • Dec. 5 at Seattle
  • Jan. 9 at Los Angeles Rams

All four teams in the NFC West are good enough to win the division. If SF can beat their division opponents, they should be in line to make the playoffs.    

What are the two most important keys for a San Francisco 49ers’ Super Bowl victory?

Quarterback Jimmy Garoppolo mustn’t get hurt. Injury-prone Jimmy G. has the talent to win the Super Bowl. He took the Niners to the 2019 game where Patrick Mahomes and the Chiefs rallied to win the Vince Lombardi Trophy.

Back-up Trey Lance will turn into a terrific quarterback. But he won’t for a while. If Garoppolo gets injured again, San Francisco will again struggle.

The second key is for the defense to gel. The defense is different than in the past few years. DT Solomon Thomas is now with the Las Vegas Raiders. Emmanuel Moseley is now the starting cornerback. 

We don’t know how good San Francisco’s defense is until it plays. 

Are the current Super Bowl odds on San Francisco fair or unfair?

The teams offering lower odds on MyBookie than the San Francisco 49ers are the Kansas City Chiefs at +500, the Tampa Bay Buccaneers at +550, the Buffalo Bills at +1100, and the Los Angeles Rams at +1100.

The 49ers have a schedule that should lead to a 14-3 or 13-4 season. If everyone stays healthy and the defense gels, SF is good enough to win the Super Bowl. So, yes, the +1200 MyBookie odds on the 49ers to win the Super Bowl are fair. 


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