Thanksgiving Game: 49ers vs Seahawks Odds and Betting Analysis for Week 12

Thanksgiving Game: 49ers vs Seahawks Odds and Betting Analysis for Week 12

One of the NFC’s best rivalries takes place on Thanksgiving Thursday’s evening matchup when the Seattle Seahawks host the San Francisco 49ers. The Seahawks host the Niners a massive +7 home dog.

Will Seattle show the oddsmakers and SF backers that making them a dog on their field was the wrong move? Or will San Francisco continue their impressive play with another win and cover?

Check out NFL odds, plus an analysis of the game with a free pick for Thanksgiving’s San Francisco at Seattle blast.

 

Thanksgiving Game: 49ers vs Seahawks Odds and Betting Prediction for this Week 12 Matchup | MyBookie NFL Regular Season Preview

San Francisco 49ers vs Seattle Seahawks | NFL Week 12 Thanksgiving Games
ATS Odds: 49ers -7
Money line Odds: Seahawks +265 / 49ers -340
Over/Under Odds: 43.5

Thursday, November 23rd, 2023 at 8:20 pm ET | NBC / Peacock
Lumen Field, Seattle, WA

 

San Francisco 49ers Offense

San Francisco boasts one of the league’s most balanced offenses. The 49ers’ passing and rushing attacks are equally effective.

Although Brock Purdy is a young quarterback, he plays like a 10-year veteran. Purdy has thrown for 2,662 yards and 18 touchdowns to just 5 interceptions. Brock completed over 84% of his passes against the Tampa Bay Buccaneers in San Francisco’s last, a 27-14 victory.

Christian McCaffrey leads a rushing attack that averages close to 134 yards per game. McCaffrey has already rushed for over 800 yards and scored 9 rushing touchdowns.

Deebo Samuel, Brandon Ayuik, and Greg Kittle make for one of the best receiving corps in the NFL. When the offensive line, led by future hall of famer Trent Williams, is healthy, look out. The 49ers can easily score more than 30 points.

San Francisco 49ers Offensive Averages

  • Total Yards: 387.0
  • Passing Yards: 254.3
  • Rushing Yards: 132.7
  • Points Scored: 27.9
  • Turnovers: 9

San Francisco 49ers Offensive Starters

  • QB Brock Purdy
  • RB Christian McCaffrey
  • WR Deebo Samuel
  • WR Brandon Ayuik
  • WR Jajuan Jennings
  • TE Greg Kittle
  • LT Trent Williams
  • LG Jon Feliciano
  • C Jake Brendel
  • RG Jaylon Moore
  • RT Colton McKivitz
 

San Francisco 49ers Defense

San Francisco’s defense has begun to creep up to where it usually resides, ranked first in the NFL. The Niners rank fifth in total yards allowed per and third in rushing yards allowed per.

But San Francisco ranks first in points allowed per game and, in arguably the most important category, first in takeaways. The Niners have produced 19 takeaways this season.

Fred Warner is one of the best linebackers in the league while Nick Bosa and Chase Young, former Ohio State teammates in college, makes for the best tandem of defensive ends in football. The secondary is also incredibly talented.

San Francisco 49ers Defensive Averages

  • Total Yards: 302.8
  • Passing Yards: 221.4
  • Rushing Yards: 81.4
  • Points Scored: 15.7
  • Takeaways: 19

San Francisco 49ers Defensive Starters

  • LDE Chase Young
  • LDT Arik Armstead
  • RDT Javon Hargrave
  • RDE Nick Bosa
  • WLB Dre Greenlaw
  • MLB Fred Warner
  • SLB Oren Burks
  • LCB Charvarious Ward
  • SS Ji’Aiyir
  • FS Tashaun Gipson Jr.
  • RCB Deommodore Lenoir
 

Seattle Seahawks Offense

Seattle’s offense ranks in the top 20 in yards per game, but the Seahawks only score 21.6 points per matchup. One of the problems is that Seattle rushes on average for less than 97 yards each game.

The rushing woes are inexplicable. Kenneth Walker is a terrific running back. Charles Cross is one of the best offensive lineman in the NFL.

Geno Smith has had a decent season, but he hasn’t come close to the 2022 season stats. Geno has thrown 7 picks to just 12 TDs. Smith completed just 64% of his passes in Seattle’s last game, a surprising 17-16 loss to the Rams.

Seattle Seahawks Offensive Averages

  • Total Yards: 327.4
  • Passing Yards: 230.8
  • Rushing Yards: 96.6
  • Points Scored: 21.6
  • Turnovers: 11

Seattle Seahawks Offensive Starters

  • QB Geno Smith
  • RB Kenneth Walker III
  • WR DK Metcalf
  • WR Tyler Lockett
  • WR Jaxon Smith-Njigba
  • TE Noah Fant
  • LT Charles Cross
  • LG Damien Lewis
  • C Evan Brown
  • RG Phil Hayes
  • RT Jason Peters
 

Seattle Seahawks Defense

Re-signing Seahawks legend Bobby Wagner has helped Seattle against the rush. However, the Hawks allow 21.8 points per game, which is .2 points more than what Seattle scores on offense.

The defense gives up 233 passing yards per game. Sometimes, the defense is plain bad like in the 31-13 home loss to the Rams in NFL Week 1 or the 37-3 loss to the Ravens.

Other times this season, the defense has stepped it up. Overall, Seattle’s defense is difficult to trust.

Seattle Seahawks Defensive Averages

  • Total Yards: 345.6
  • Passing Yards: 233.0
  • Rushing Yards: 112.6
  • Points Scored: 21.8
  • Takeaways: 14

Seattle Seahawks Defensive Starters

  • LDE Dre’Mont Jones
  • NT Jarran Reed
  • RDE Leonard Williams
  • WLB Boye Mafe
  • LILB Jordan Brooks
  • RILB Bobby Wagner
  • SLB Darrell Taylor
  • LCB Devon Witherspoon
  • SS Jamal Adams
  • FS Quandre Diggs
  • RCB Riq Woolen
 

Seattle Seahawks vs San Francisco 49ers Final Betting Prediction

One team is on a slide and the other is motoring. Seattle remains a game behind San Francisco in the NFC West but the Seahawks have lost 2-of-3 and are 3 points away from going 0-3 straight up in their last 3.

The win, a 29-26 game versus Washington, didn’t impress. The Seahawks defense struggled to get to Sam Howell. On Thursday Night Football, Seattle faces one of the best offensive lines in football.

Getting to Brock Purdy will be a massive challenge. So we shouldn’t hold our breath and expect the Seahawks to suddenly wake up and stop one of the top offenses in football. Purdy, Deebo, McCaffrey and Kittle should dominate.

Also, a couple of weeks ago in Jacksonville, San Francisco showed they can take their excellent play on the road. SF wins and covers.

2023 NFL Thanksgiving Pick: ATS San Francisco 49ers -7 | Bet 49ers vs Seahawks
MyBookie Betting Lines for the Game


 

San Francisco 49ers Team

7-3 | 3-2 Away

 

San Francisco 49ers Last 5

Date OPP Result
11/19/23 vs TB W27-14
11/12/23 @ JAX W34-3
10/29/23 vs CIN L31-17
10/22/23 @ MIN L22-17
10/15/23 @ CLE L19-17

San Francisco 49ers Injury Report

Name | Position Status Date
Aaron Banks G Questionable Nov 21
Ray-Ray McCloud III WR Questionable Nov 21
Shemar Jean-Charles CB Questionable Nov 20
Javon Hargrave DT Questionable Nov 20
Spencer Burford OT Questionable Nov 20
 

Seattle Seahawks Team

6-4 | 4-1 Home

 

Seattle Seahawks Last 5

Date OPP Result
11/19/23 @ LAR L17-16
11/12/23 vs WSH W29-26
11/5/23 @ BAL L37-3
10/29/23 vs CLE W24-20
10/22/23 vs ARI W20-10

Seattle Seahawks Injury Report

Name | Position Status Date
Dareke Young WR Questionable Nov 21
Jamal Adams S Questionable Nov 21
Jerrick Reed II S Questionable Nov 20
Jake Bobo WR Questionable Nov 20
Riq Woolen CB Questionable Nov 20
 

2023 NFL Standings up to Week 12

NFC West Standings

Team W L PCT Strk
San Francisco 49ers 7 3 .700 W2
Seattle Seahawks 6 4 .600 L1
Los Angeles Rams 4 6 .400 W1
Arizona Cardinals 2 9 .182 L1

NFL Odds

Super Bowl Odds to Win:
49ers +430 | Seahawks +4200

NFC Conference Odds to Win:
49ers +216 | Seahawks +2200

 

San Francisco 49ers vs Seattle Seahawks Betting Trends

  • San Francisco are 2-5 ATS in their last 7 games on the road.
  • San Francisco are 2-10 SU in their last 12 games when playing on the road against Seattle.
  • San Francisco are 14-2 SU in their last 16 games against an opponent in the National Football Conference conference.
  • San Francisco are 10-1 ATS in their last 11 games against an opponent in the National Football Conference West division.
  • The total has gone UNDER in 4 of San Francisco’s last 5 games played in November.
  • Seattle are 10-2 SU in their last 12 games when playing at home against San Francisco.
  • Seattle are 5-1 ATS in their last 6 games against an opponent in the National Football Conference conference.
  • The total has gone UNDER in 5 of Seattle’s last 6 games against an opponent in the National Football Conference West division.
  • Seattle are 2-8 ATS in their last 10 games played in November.
  • The total has gone UNDER in 7 of Seattle’s last 9 games played on a Thursday.
 
 

The following NFL betting odds are based on MyBookie Sportsbook.

Super Bowl Odds to Win this 2025 NFL Season

Teams Odds
San Francisco 49ers +550
Kansas City Chiefs +700
Baltimore Ravens +800
Buffalo Bills +1000
Detroit Lions+1200
Cincinnati Bengals +1300
Dallas Cowboys +1600
Philadelphia Eagles +1800
Miami Dolphins +2000
Green Bay Packers +2200
Houston Texans +2200
LA Chargers +2500
New York Jets +2500
Jacksonville Jaguars +3500
Los Angeles Rams +3500
Cleveland Browns +4000
Minnesota Vikings +4000
Atlanta Falcons +5000
Chicago Bears +5000
Indianapolis Colts +5000
Denver Broncos +7500
Las Vegas Raiders +7500
New Orleans Saints +7500
Pittsburgh Steelers +7500
Seattle Seahawks +7500
Tampa Bay Buccaneers +7500
Arizona Cardinals +10000
New England Patriots +15000
New York Giants +15000
Tennessee Titans +15000
Washington Commanders +15000
Carolina Panthers +25000

Bet Super Bowl Lines to Win


 

I have read enough, I need to place my bet now. What to do?

NFL Odds
MyBookie Lines for the Games

 

NFL Betting Center


NFL MyBookie Odds | Online Betting Lines