Monday, October 13, 8:30 PM on ESPN, Edward Jones Dome, St. Louis, MissouriFor the 49ers, this game has a different meaning, but a victory against a divisional will help the team to improve its postseason chances and keep their momentum after vital wins against the Philadelphia Eagles and Kansas City Chiefs. San Francisco opened the season in great fashion, delivering a setback to the Dallas Cowboys in Arlington, TX, but two consecutive losses to Chicago and Arizona put their postseason plans in peril, brought many questions around Colin Rand Kaepernick’s ability as offensive leader and put head coach Jim Harbaugh against the wall.
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