College Football Games to Bet On With the Highest Stakes on the Calendar

The college football season will feature more than 1,000 games played between teams nationwide. However, when it comes to the impact on the College Football Playoff, a handful of games have a major impact on the playoff picture. Those are the games that typically generate the highest betting interest.

Check out a list of the four college football games that gridiron handicappers must have on their radar so you can plan your bets against the NCAAF lines. 

College Football Games to Bet On With the Highest Stakes on the Calendar | MyBookie Betting Preview

2023 NCAA Division I FBS season | 154th season of college football
August 26, 2023 – December 9, 2023

Texas Longhorns at Alabama Crimson Tide | NCAAF Week 2

Saturday, September 9, 2023
Bryant-Denny Stadium | Tuscaloosa, AL

The Texas Longhorns are coming off a disappointing season where their most impressive performance may have come in a loss. Texas gave up a late field goal and lost 20-19 to the Alabama Crimson Tide in Austin. Now, Texas will make the return trip to play the Crimson Tide on Sept. 9.

Both teams are hoping to use this as a springboard to the CFP. Alabama will have a new starting quarterback this season, while the Longhorns will have Quinn Ewers returning to run the offense. This will be a fun meeting where Alabama is a 7-point favorite in the preseason.

Bet Texas at Alabama
MyBookie Betting Lines for the Championship

LSU Tigers at Florida State Seminoles | NCAAF Week 1

Sunday, September 3, 2023
Camping World Stadium | Orlando, FL

The LSU Tigers and Florida State Seminoles played a classic season-opener last season in New Orleans. Florida State escaped with a one-point win when LSU missed an extra point as time expired. The Seminoles and Tigers both went on to have double-digit win seasons. LSU went on to win the SEC West.

Now, both programs will meet in Orlando with the Tigers being installed as a 3-point favorite. LSU and Florida State return talent at quarterback and should produce another interesting contest.

Bet LSU at Florida State
MyBookie Betting Lines for the Championship

Ohio State Buckeyes at Michigan Wolverines | NCAAF Week 13

Saturday, November 25, 2023
Michigan Stadium | Ann Arbor, MI

The Ohio State Buckeyes and Michigan Wolverines both made the CFP last season. However, during the regular season, it was Michigan that rolled up another big victory over the Buckeyes to go on to their second consecutive Big Ten crown. The Wolverines have now won two straight games against Ohio State.

The Wolverines will be under pressure to maintain that success here. Since the teams don’t meet until Nov. 25, there is a lot that could change between now and the end of the season. However, this will be a game that should be exciting to bet on.

Bet Ohio State at Michigan
MyBookie Betting Lines for the Championship

Penn State Nittany Lions at Ohio State Buckeyes| NCAAF Week 8

Saturday, October 21, 2023
Ohio Stadium | Columbus, OH

The Big Ten East Division will be one that produces several intriguing matchups with several long-term consequences. Penn State will have to travel to Ohio State on Oct. 21 to try and stake its claim to a spot in the division race. This is a game that had been historically close until recently.

The Buckeyes lead the all-time series 23-14, including a string of six straight victories in the series. Penn State has a roster full of young talent that needs to prove itself on the big stage. The Penn State Nittany Lions and Buckeyes will produce an interesting game that will change the playoff picture.

Bet Penn State at Ohio State
MyBookie Betting Lines for the Championship

NCAA College Football National Championship Odds Top 20

I have read enough, I need to place my bet now. What to do?

Bet College Football Today
MyBookie Odds for the Games

NCAA Football Betting Center

---

Updated College Football Betting Odds | Online Sports Betting

mybookie App Download App

Download Remind me later