Louisville at Clemson Betting Pick & Prediction

We all thought that the Oct. 29 matchup between Clemson and Florida State might be the game of the year in college football and determine the ACC champion. That game won’t mean too much if No. 3 Louisville goes to No. 5 Clemson on Saturday and beats the Tigers, who are very rare home underdogs in college football lines.

Here’s a Sneak Peek at the Louisville at Clemson Betting Pick, Prediction & TV Info

When: Saturday, Oct. 1, 8 PM ET Where: Memorial Stadium, Clemson TV: ABC Stream: WatchESPN Radio: Louisville / Clemson Opening NCAA Football Lines: Louisville -2 (67.5)

Why Bet on Louisville?

Because Lamar Jackson has been responsible for 25 touchdowns, by far the most in the nation and more than all but one FBS team has scored overall (Michigan). Jackson is the clear Heisman Trophy favorite and he can probably lock up the award with a huge game and win here. The Cardinals (4-0) are off a 59-28 win at Marshall in what could have been a trap game. Jackson threw five touchdown passes and ran for two more. The sophomore completed 24 of 44 passes for a career-high 417 yards against a Marshall secondary whose most experienced player had five starts. Jackson also ran for 62 yards. Jackson’s scoring passes covered 71, 8, 30, 8 and 51 yards. After four games, he’s thrown 13 TD passes and run for 12 more scores. The Cardinals have scored 59 or more points in four straight games this season. Louisville is one of four teams since 1920 to score 59 or more points in four consecutive games (Oklahoma 2008, Baylor 2013, Baylor 2105). Louisville extended its school-record streak of consecutive games with 250 or more yards rushing to six games with 273 on the ground versus Marshall. The Cardinals accumulated over 500 yards of total offense for the fifth-straight game dating back to last season’s Music City Bowl win over Texas A&M. The 690 yards of total offense is the seventh-highest in school history. Jackson has accounted for 12.8 quarterback points added per game, the most value for any quarterback in the first four games in the past 10 seasons. His completion percentage has jumped from 54.7 last season to 58.7 so far this year. He has already accounted for 72.3 percent of his passing output from 2015, and has eclipsed his passing touchdowns total from last season (12) with 13. The Cardinals, who are 0-2 all-time against Clemson, have dropped both games by a combined nine points, including a 23-17 defeat in Clemson in 2014, with the ball sitting on the Tigers’ 2-yard line on the game’s final play.

Why Bet on Clemson?

The Tigers (4-0) have been off since beating Georgia Tech 26-7 last Thursday. Brent Venables’ defense allowed only 22 yards of total offense in the opening half and 124 for the game. Offensively, the Tigers were efficient in the opening half behind the passing of Deshaun Watson, who was 32-for- 48 for a season-high 304 yards and two touchdowns. The Tigers’ dominance was on display in the opening half. Clemson ran 56 total plays, compared to just 21 for Tech. The Yellow Jackets were stuffed for only 22 total yards, most of which came on the final play before halftime. The Tigers snapped a five-game losing skid in the series in Bobby Dodd Stadium. Clemson’s last win in Atlanta prior to Thursday came in 2003, when co-offensive coordinator Tony Elliott was a senior wide receiver for the Tigers. Clemson is now 71-6 under head coach Dabo Swinney win outgaining the opponent in total offense. The Tigers are now 65-7 all time under Swinney when leading at halftime and 70-4 when leading heading into the fourth quarter. Last year, Clemson won at Louisville 20-17. Clemson’s defense held Louisville’s offense to just 272 yards, including just 19 rushing, and allowed just one offensive touchdown. Wayne Gallman was the star for the Tigers with 24 carries for 139 yards. Watson completed 21-for- 30 passes for 199 yards and two  scores. Clemson gained 401 yards total, 202 rushing and 199 passing in 70 plays, a 5.7 average. While this is just the second top five matchup in the history of Memorial Stadium, it is the fifth meeting of top 12 teams in Memorial Stadium in the last five years. Clemson has won two of the previous four, a win over Georgia in 2013 and the win over Notre Dame last year.

My Betting Pick

Cardinals are 1-5 ATS in their last 6 games in October. Tigers are 5-1 ATS in their last 6 games following a straight up win. Tigers are 4-1 ATS in their last 5 home games. Lean Clemson and the over in NCAA football lines.