Jacksonville at San Francisco NFL Lines & Week 16 Prediction
When: Sunday, 4:05 PM ET Where: Levi’s Stadium, Santa Clara, Calif. TV: CBS Radio: 1010 XL (Jacksonville) / KNBR 680 (San Francisco) Opening NFL Lines: Jaguars -4 (42)Weather Forecast
- Partly Cloudy: 15°C/59°F
- Humidity: 37%
- Precipitation: 0%
- Wind: 6 mph NNW
- Cloud Cover: 58%
- Type of Stadium: Open
Last Meeting
Sunday marks the fifth-overall meeting between the 49ers and Jaguars, with each team splitting the series at 2-2. The 49ers host Jacksonville for the first time at Levi’s Stadium, and their first home matchup since 2009. San Francisco is looking for its third consecutive victory over the Jaguars. In 2013, the Jaguars lost to the Niners 42-10. That game was in London. San Francisco QB Colin Kaepernick had 164 yards passing and 54 yards rushing, Frank Gore also ran for two scores and 71 yards. Kaepernick is out of the NFL now and Gore with the Colts. Chad Henne was the Jags’ QB.Latest NFL Betting Trends
- Jacksonville is 4-1 ATS in its last 5 games
- Jacksonville is 7-1 SU in its last 8 games
- The total has gone UNDER in 5 of Jacksonville’s last 7 games on the road
- San Francisco is 4-1 SU in its last 5 games
- San Francisco is 5-20 SU in its last 25 games
- The total has gone UNDER in 5 of San Francisco’s last 7 games