This Sunday, the Las Vegas Raiders embark on a cross-country journey to face off against the Buffalo Bills in what promises to be an intriguing matchup.
The Raiders find themselves in an enviable 1-0 position to start the season, having secured a significant upset over the Denver Broncos in Week One, a feat that makes them the sole victors in the fiercely competitive AFC West.
Meanwhile, the Buffalo Bills had a less fortunate start, as they find themselves at 0-1. Their opening game witnessed a heartbreaking turn of events as they squandered a lead and eventually succumbed to a surprising overtime loss at the hands of the New York Jets.
Star quarterback Josh Allen encountered substantial difficulties in the loss, and the Bills missed a golden opportunity when Aaron Rodgers exited the game for the Jets.
The Buffalo Bills are big favorites in this game. Despite being 0-1 and playing a team that is 1-0, the Bills are -9.5 over the Raiders. The total for this game is 47 points.
Check out NFL Week 2 betting odds, analysis, and free picks for Las Vegas Raiders versus the Buffalo Bills.
Raiders vs Bills Odds and Betting Prediction for the Game | MyBookie NFL Week 2 Regular Season Preview
Las Vegas Raiders vs Buffalo Bills | NFL Week 2
ATS Odds: Bills -9.5
Money line Odds: Raiders +330 / Bills -450
Over/Under Odds: 47
Sunday, September 17th at 1:00 pm ET | CBS
Highmark Stadium, Orchard Park, NY
Raiders Seeking 2-0 Start
Week One marked a significant victory for the Las Vegas Raiders, although it was far from a flawless performance. The Raiders secured the win, but it was not without its share of challenges.
The newly-acquired quarterback, Jimmy Garoppolo, played a pivotal role by throwing two touchdowns and amassing 200 passing yards. His primary target, Jakobi Meyers, made a noteworthy impact before being sidelined with a concussion, ultimately recording 200 receiving yards and two touchdowns.
On the flip side, the Raiders faced difficulties in their ground game. Josh Jacobs, who had previously led the NFL in rushing yards, struggled to gain momentum, finishing with just 48 yards on 19 carries. Their rushing performance in the opening week ranked a modest 28th in the league.
As the Raiders prepare for their upcoming game, they will need to address offensive issues from Week One. They have a challenging schedule ahead, with a home matchup against the Pittsburgh Steelers in Week 3, followed by a crucial divisional clash with the Los Angeles Chargers on the road in Week 4.
Improvements on the offensive front will be paramount for the Las Vegas Raiders as they aim for success in their Week Two showdown against the Buffalo Bills.
Bills Frustrated with Opener
The Buffalo Bills undoubtedly faced one of the most surprising disappointments in Week One, primarily due to the game’s outcome. Despite holding a lead and forcing Aaron Rodgers to exit after just four snaps, the Bills fell short in overtime against the New York Jets.
Josh Allen, their star quarterback, experienced a rough outing, plagued by three interceptions and enduring five sacks. To compound matters, he also lost a fumble late in the fourth quarter, which ultimately allowed the Jets to regain possession. This performance dealt a blow to any aspirations Josh Allen may have had of securing favorable NFL MVP Odds.
In terms of offensive highlights for the Bills, Stefon Diggs emerged as a beacon of consistency, racking up ten receptions for 102 yards and a crucial touchdown. He stood as the lone receiver to eclipse the 32-yard mark in the game for Buffalo.
On the ground, James Cook carried the load, rushing 12 times for a total of 46 yards, while Allen himself contributed with 36 rushing yards early in the game.
Buffalo enters this upcoming game with a determined resolve to avoid a disheartening 0-2 start. Subsequently, they will embark on a road trip to face the Washington Commanders. Looking ahead to Week Four, the Bills will return home for back-to-back matchups against the Dolphins and Jaguars.
The Buffalo Bills’ performance and the dynamics of betting on their games will undoubtedly be closely watched until they demonstrate a turnaround and regain their winning form.
Bills Blast Raiders in Buffalo
The fans in Buffalo will be ready for the Bills to return. In the end, it was just 1 of 17 games this season for the Bills. They are now a game behind the Dolphins and the Jets. They need to make sure it’s not two.
Take the Buffalo Bills to win by double digits. Betting Buffalo -8.5 is the right bet here.
NFL Week 2 Pick: Buffalo Bills -4.5 | Bet Raiders vs Bills
MyBookie Betting Lines for the Game
Las Vegas Raiders Last 5
| Date | OPP | Result |
|---|---|---|
| 9/10/23 | @ LAR | W17-16 |
| 8/26/23 | @ GB | L31-16 |
| 8/19/23 | @ DAL | W34-17 |
| 8/13/23 | vs MIN | W34-7 |
| 1/7/23 | vs SF | L31-13 |
Las Vegas Raiders Injury Report
| Name | Position | Status | DATE |
|---|---|---|
| Tre’von Moehrig S | Questionable | Sep 10 |
| Chandler Jones DE | Questionable | Sep 12 |
| Jakobi Meyers WR | Questionable | Sep 13 |
Buffalo Bills Last 5
| Date | OPP | Result |
|---|---|---|
| 9/11/23 | @ NYJ | L22-16OT |
| 8/26/23 | @ CHI | W24-21 |
| 8/19/23 | @ PIT | L24-15 |
| 8/12/23 | vs IND | W23-19 |
| 1/22/23 | vs CIN | L27-10 |
Buffalo Bills Injury Report
| Name | Position | Status | DATE |
|---|---|---|
| No injured players | – | – |
Las Vegas Raiders at Buffalo Bills Betting Trends
- The Bills took the last 2 meetings, including the most recent tilt 30-23 as 3-point home favorites Oct. 4, 2020 — the Over/Under pushed at 53.
- At home last season, Buffalo was 7-1 overall and 4-4 against the spread.
- The Bills had eight wins in 16 games against the spread last year.
- At home last season, Buffalo had two wins ATS (2-2) as 9.5-point favorites or more.
- The Raiders last win in the series was 38-24 victory — also as 3-point home favorites — Dec. 4, 2016.
- The Bills are 4-2 in the last 6 meetings, including 3-0 at home.
- The Raiders’ last win in Buffalo came in 2002, a 49-31 victory as 3-point favorites.
- The Over has hit 7 games in a row in the series and is 8-2 in the last 10 meetings.
The following NFL betting odds are based on MyBookie Sportsbook.
Super Bowl Odds to Win this 2025 NFL Season
The following NFL betting lines are based on MyBookie Sportsbook.
| Teams | Odds |
|---|---|
| Kansas City Chiefs | +480 |
| San Francisco 49ers | +520 |
| Baltimore Ravens | +930 |
| Philadelphia Eagles | +960 |
| Detroit Lions | +990 |
| Buffalo Bills | +1175 |
| Houston Texans | +1300 |
| Dallas Cowboys | +1475 |
| New York Jets | +1475 |
| Cincinnati Bengals | +1625 |
| Miami Dolphins | +2300 |
| Atlanta Falcons | +2900 |
| Los Angeles Rams | +3000 |
| Chicago Bears | +3100 |
| Green Bay Packers | +3100 |
| Los Angeles Chargers | +3200 |
| Cleveland Browns | +3900 |
| Pittsburgh Steelers | +4100 |
| Jacksonville Jaguars | +4500 |
| New Orleans Saints | +4900 |
| Minnesota Vikings | +5400 |
| Seattle Seahawks | +5800 |
| Tampa Bay Buccaneers | +6200 |
| Indianapolis Colts | +8000 |
| Las Vegas Raiders | +9000 |
| Arizona Cardinals | +11000 |
| Washington Commanders | +13000 |
| Denver Broncos | +14000 |
| New England Patriots | +14000 |
| Tennessee Titans | +16000 |
| New York Giants | +17000 |
| Carolina Panthers | +40000 |
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