NFL Week 1 Odds, 49ers vs Bears Betting Prediction

The San Francisco 49ers begin their Super Bowl quest on the road in week 1 versus the Chicago Bears. SF starts the season with a news starter at quarterback, Trey Lance. Will Lance show that benching Jimmy Garoppolo was the right move? How will Justin Fields play for the Bears in his first game after his rookie season? Keep reading for NFL Odds, analysis, and a free pick for Chicago versus San Francisco.

NFL San Francisco 49ers at Chicago Analysis and Odds Preview | Week 1 Betting Predictions

NFL Week 1 San Francisco versus Chicago Match Info and Odds

When: Sunday, Sep. 11 at 1:00 pm ET
Where: Soldier Field, Chicago, IL
TV / Streaming: FOX / Fox Sports
ATS Odds: San Francisco -7
Moneyline Odds: San Francisco -309 / Chicago +240
Over/Under Odds: 41.5

Why bet on San Francisco versus Chicago?

Few teams have as talented of a roster as the San Francisco 49ers. Trey Lance has the makings of the next Patrick Mahomes. Deebo Samuel, who signed a massive extension during the offseason, might be the most unique skill player in the league. SF’s defense allowed around 21 points per game last season. On Sunday, the D faces one of the worst offenses in 2021.

San Francisco 49ers Offensive Averages

** Stats from 2021

Total Yards: 375.7

Passing Yards: 248.3

Rushing Yards: 127.4

Points Scored: 25.1

Turnovers: 24

San Francisco 49ers Defensive Averages

** Stats from 2021

Total Yards: 310.0

Passing Yards: 206.5

Rushing Yards: 103.5

Points Scored: 21.5

Takeaways: 17

Why bet on Chicago versus San Francisco?

The 2022 Bears is a galaxy away from the 2021 squad. Chicago won all 3 of their preseason games. Although preseason games are meaningless, winning all 3 is a sign the Bears are a cohesive unit. Justin Fields is no longer a rookie and the defense should be as solid as it was last season. Also, Chicago gets 7 points and this game happens at Solder Field.

Chicago Bears Offensive Averages

** Stats from 2021

Total Yards: 307.4

Passing Yards: 188.6

Rushing Yards: 118.7

Points Scored: 18.3

Turnovers: 29

Chicago Bears Defensive Averages

** Stats from 2021

Total Yards: 316.7

Passing Yards: 191.6

Rushing Yards: 125.1

Points Scored: 23.9

Takeaways: 15

49ers at Bears Relevant Trends

49ers are 5-0 ATS in their last 5 games
San Francisco is 6-1 ATS in their last 7 games on grass
Under is 7-1 in San Francisco’s last 8 games
Bears are 0-6 ATS in their last 6 games as a home underdog
Chicago is 3-9 ATS in their last 12 games
Over is 4-1 in the Bears’ last 5 games as an underdog

San Francisco 49ers at Chicago Bears Final Betting Prediction

It’s never fun to lay 7 points, but in this case, it’s not possible to back the Chicago Bears. The problem Chicago will have in this game is two-fold.

First, the Bears’ won’t stop Trey Lance, running back Elijah Mitchell, and the best skill player in the NFL, Deebo Samuel. It says in Deebo’s contract that he can make more depending on how well he plays as a running back.

Coach Kyle Shanahan is going to use Deebo in so many ways our heads are going to spin. Not only that, but Lance is more versatile than Garoppolo and Mitchell should see daylight behind one of the league’s top offensive lines.

Fields will play better this season than last. But Darnell Mooney may not be a legit WR1, we must question the offensive line, and linebacker Roquan Smith doesn’t seem happy. SF wins and covers.

NFL Week 1 Pick: San Francisco 49ers -7

I have read enough, I need to place my bet now. What to do?