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The San Francisco 49ers head to Las Vegas to take on the former Bay Area rival Raiders looking for their ninth straight victory. Rookie quarterback Brock Purdy is playing like a five year vet while the SF defense is dominating. Will a quarterback for Vegas lead to a win against the spread? Or will the Niners cover their seventh in a row? Keep reading for NFL Odds, analysis, and a free pick for San Francisco at Las Vegas.

NFL Week 17 Betting Preview and Prediction for San Francisco 49ers at Las Vegas

San Francisco 49ers versus Las Vegas Raiders Lines and Match Info

When: Sunday, Jan. 1 at 4:05 pm ET
Where: Allegiant Stadium, Las Vegas, NV
TV / Streaming: FOX
ATS Odds: San Francisco -9.5
Money line Odds: Las Vegas +380 / San Francisco -526
Over/Under Odds: 42.5

Why bet on San Francisco versus Las Vegas?

The 49ers are gearing up for a deep playoff run. The one question was whether Brock Purdy could pick up where Jimmy G. and the offense had left off.

After Garoppolo went down with an injury, some put a fork into the 49ers. All Purdy has done is play like he has been in Kyle Shanahan’s offensive system for the past decade. Purdy has an 8 TD to 3 INT ratio, completes over 67% of his passes, and has thrown for over 900 yards in less than 4 starts.

San Francisco 49ers Offensive Averages

Total Yards: 363.4

Passing Yards: 228.7

Rushing Yards: 134.7

Points Scored: 25.0

Turnovers: 16

San Francisco 49ers Defensive Averages

Total Yards: 290.3

Passing Yards: 215.3

Rushing Yards: 75.0

Points Scored: 15.3

Takeaways: 22

Why bet on Las Vegas versus San Francisco ?

Josh McDaniel benched quarterback Derek Carr, which explains why the line moved from SF -6 to 49ers -9.5. Carr is the much more accomplished quarterback than Jarrett Stidham.

But Stidham knows McDaniels’ system better than Carr does. Josh is trying to fire up his offense. He realizes how good the Niners are versus the rush. The gambit could pay off with at least a cover victory.

Las Vegas Raiders Offensive Averages

Total Yards: 347.6

Passing Yards: 225.9

Rushing Yards: 121.7

Points Scored: 23.2

Turnovers: 17

Las Vegas Raiders Defensive Averages

Total Yards: 360.9

Passing Yards: 244.3

Rushing Yards: 116.6

Points Scored: 23.3

Takeaways: 12

49ers at Raiders Relevant Trends

49ers are 5-1 ATS versus a team with a losing record
San Francisco is 5-0 ATS in their last 5 games on grass
Over is 6-1 in the 49res’ last 7 games on the road versus a team with a losing record at home
Raiders are 5-0 ATS versus a team with a winning record
Las Vegas is 4-1 ATS in their last 5 at home
Over is 4-1 in the Raiders’ last 5 games at home

San Francisco 49ers at Las Vegas Raiders Final Betting Prediction

San Francisco steam rolls opponents, but in this case, the line has moved too much. The game happens in Vegas where the Raiders are a terrific 4-2 against the spread.

McDaniels is trying to switch up his offense. The problem is that Carr wasn’t running the O the way Josh wanted, which makes sense.

That doesn’t mean Vegas wins this game. In fact, when it was 6 points, the Niners were a terrific play. SF should get a touchdown and extra point lead.

But pushing the lead to 10 on the road versus a team with a top defensive end like Maxx Crosby and against a signal-caller who is familiar with the playing calling head coach is asking too much. The Raiders cover.

NFL Week 17 Pick: Las Vegas Raiders +9.5