NFL Monday Night Football: Buffalo Bills at Tennessee Betting Analysis

The new Super Bowl LVI favorite heads to Nashville on Monday night to tackle the strong Tennessee Titans. Can Buffalo show they’ve got what it takes to stop Derrick Henry and Tennessee’s fast moving offense? Or will the Titans’ defense step it up enough to take down the vaunted Bills? See below for NFL odds, analysis, and a free pick for Buffalo at Tennessee on NFL Monday Night Football.

NFL Betting Preview for Buffalo Bills vs Tennessee Titans

NFL Week 6: Buffalo at Tennessee Game Odds & Info

When: Monday, Oct. 18 at 8:15 pm ET
Where: Nissan Stadium, Nashville, TN
TV / Streaming: ESPN / ESPN+
ATS Odds: Buffalo -5 ½
Moneyline Odds: Buffalo -255 / Tennessee +205
Over/Under Odds: 54

Why bet on Buffalo versus Tennessee?

The Bills have become one of the favorites to win the Super Bowl. Right now, no team can touch Buffalo. How dominant have the Bills been this season? Heading into NFL Week 6, Buffalo ranks first in points scored per. They also rank first in points allowed each game. Unless the Bills aren’t prepared they should easily handle the spread.

Buffalo Bills Offensive Averages

Total Yards: 410.4

Passing Yards: 270.0

Rushing Yards: 140.4

Points Scored: 34.4

Turnovers: 4

Buffalo Bills Defensive Averages

Total Yards: 251.8

Passing Yards: 173.4

Rushing Yards: 78.4

Points Scored: 12.8

Takeaways: 13

Why bet on Tennessee versus Buffalo?

Tennessee’s offense can score with the Bills. More importantly, the Titans send the top running back in the game onto the field. Derrick Henry can slash his way through any defense on the planet. If Buffalo gets into a coverage scheme on defense, a cover 2 or cover 3, the Titans will hand the ball off to Henry and allow him to rumble at will. If Henry is allowed to carry the load, he’ll take time off the clock, increasing Tennessee’s chance to not only cover, but to also win the game.

Tennessee Titans Offensive Averages

Total Yards: 389.2

Passing Yards: 221.4

Rushing Yards: 167.8

Points Scored: 26.4

Turnovers: 7

Tennessee Titans Defensive Averages

Total Yards: 377.4

Passing Yards: 264.6

Rushing Yards: 112.8

Points Scored: 26.0

Takeaways: 4

Bills at Titans Relevant Trends

Bills are 5-1 ATS in their last 6 games on grass
Buffalo is 13-3 ATS in their last 16 games
Over is 7-1-1 in the Bills last 9 games on grass
Titans are 7-2 ATS in their last 9 games on a Monday night
Underdog is 6-0 ATS in the last 6 meetings
Over is 7-1 in the Titans last 8 games as an underdog

Buffalo Bills versus Tennessee Titans Final Betting Prediction

Henry is a tough running back, but Buffalo’s defense yields 78.4 rushing yards per. Tennessee can throw the ball. So the Titans will switch it up if the Bills key on stopping Henry.

From a Titans point-of-view, they’re up against it on the defensive side. Josh Allen is making a case as the league’s MVP. Allen can play in the pocket, move out of the pocket, or run with the ball.

He’s got enough skills to adjust to anything the Titans do on defense. More importantly, Buffalo is locked in right now. They aren’t taking prisoners on their way to what they believe is home field advantage and a spot in Super Bowl 56.

The Bills are the best team in the NFL. They could play a bad game after so thoroughly destroying the Kansas City Chiefs in NFL Week 5. The thinking here, though, is that Buffalo rolls to another win and cover.

NFL Week 6 Pick: Buffalo Bills

I have read enough, I need to place my bet now. What to do?