One of the NFC’s top rivalries resumes on Sunday in NFL Week 1 when the L.A. Rams head to the Emerald City to take on the Seattle Seahawks. The Seahawks made the playoffs last season. So high hopes exist for Seattle in 2023.
Will the Rams prove best as a +4.5 dog? Or will Seattle win and cover?
Check out NFL Week 1 betting odds, analysis, and free picks for Seattle versus the Los Angeles Rams.
Rams vs Seahawks Odds and Betting Prediction for the Game | MyBookie NFL Week 1 Regular Season Preview
Los Angeles Rams vs Seattle Seahawks | NFL Week 1
ATS Odds: Seattle -4.5
Money line Odds: Rams +177 / Seahawks -222
Over/Under Odds: 46
Sunday, Sep 10 at 4:25 pm ET | FOX
Lucas Oil Stadium, Seattle, IN
Why Bet on Rams versus Seahawks?
Matthew Stafford was hurt for most of last season. Staff is one-hundred percent healthy. The likely future hall of fame quarterback will improve the Rams offense by passing the pigskin.
Staff will also improve the Rams offense by just being on the field. Because Seattle’s porous defense must pay attention to the Rams’ passing attack, L.A. should have success rushing the football.
2022 Los Angeles Rams Offensive Averages
- Total Yards: 303.9
- Passing Yards: 182.8
- Rushing Yards: 97.7
- Points Scored: 18.1
- 3rd Down %: 39.34
2022 Los Angeles Rams Defensive Averages
- Total Yards: 355.8
- Passing Yards: 226.0
- Rushing Yards: 115.1
- Points Scored: 22.6
- 3rd Down %: 40.39
Why Bet on Seahawks versus Rams?
In 2022, Seahawks starting quarterback Geno Smith had the best season of his career. Smith is back and so are his top two targets, Tyler Lockett and the great D.K. Metcalf.
Metcalf is one of the best wide receiver in the league. Lockett can flat out fly. So after a full season together the quarterback and his wideouts should be even more effective in 2023.
Also, Seattle signed Bobby Wagner away from the Rams. Wagner is one of the greatest linebackers in Seattle Seahawks’ history. Bobby will have a massive effect on the outcome of this game.
2022 Seattle Seahawks Offensive Averages
- Total Yards: 372.0
- Passing Yards: 231.4
- Rushing Yards: 120.1
- Points Scored: 23.9
- 3rd Down %: 37.81
2022 Seattle Seahawks Defensive Averages
- Total Yards: 379.1
- Passing Yards: 211.5
- Rushing Yards: 150.2
- Points Scored: 23.6
- 3rd Down %: 42.29
Los Angeles Rams at Seattle Seahawks Final Betting Prediction
The spread line makes the Seahawks an overlay. The Rams should struggle to score more than 10 points in this game while Seattle will approach 30.
Matthew Stafford may be healthy, but the Rams will boast one of the league’s worst offensive lines. So Stafford could be evading the rush all afternoon.
Also, Bobby Wagner is one of the best run stoppers in the game, which means Seattle’s D will improve big time versus the rush. In addition, Cooper Kupp won’t play so Staff is going to struggle to find targets.
Seattle rolls in this. Don’t be surprised if the Seahawks blowout the Los Angeles Rams on Sunday.
NFL Week 1 Pick: Seattle Seahawks -4.5 | Bet Rams vs Seahawks
MyBookie Betting Lines for the Game
Los Angeles Rams Last 5
| Date | OPP | Result |
|---|---|---|
| 8/26/23 | @ DEN | L41-0 |
| 8/19/23 | vs LV | L34-17 |
| 8/12/23 | vs LAC | L34-17 |
| 1/8/23 | @ SEA | L19-16 OT |
| 1/1/23 | @ LAC | L31-10 |
Los Angeles Rams Injury Report
| Name | Position | Status | DATE |
|---|---|---|
| Shaun Jolly CB | Questionable | Sep 6 |
| Cooper Kupp WR | Questionable | Sep 8 |
| Stetson Bennett QB | Questionable | Sep 8 |
| Hunter Long TE | Questionable | Sep 8 |
Seattle Seahawks Last 5
| Date | OPP | Result |
|---|---|---|
| 8/26/23 | @ GB | L19-15 |
| 8/19/23 | vs DAL | W22-14 |
| 8/10/23 | vs MIN | W24-13 |
| 1/14/23 | @ SF | L41-23 |
| 1/8/23 | vs LAR | W19-16 OT |
Seattle Seahawks Injury Report
| Name | Position | Status | DATE |
|---|---|---|
| Devon Witherspoon CB | Questionable | Sep 6 |
| Derick Hall LB | Questionable | Sep 6 |
| Damien Lewis G | Questionable | Sep 7 |
| Kenneth Walker III RB | Questionable | Sep 7 |
| Boye Mafe LB | Questionable | Sep 7 |
Los Angeles Rams at Seattle Seahawks Relevant Trends
- Rams are 5-0 ATS in their last 5 games playing in Seattle
- Under is 4-1 in Seattle’s last 5 games
- Under is 6-2 in Seattle’s last 5 games playing the Rams
- Rams are 5-2 ATS in their last 7 games
- Over is 1-4 in the Rams’ last 5 games
- Seahawks are 1-8 ATS in their last 9 games
The following NFL betting odds are based on MyBookie Sportsbook.
Super Bowl Odds to Win this 2025 NFL Season
The following NFL betting lines are based on MyBookie Sportsbook.
| Teams | Odds |
|---|---|
| Detroit Lions | +280 |
| Kansas City Chiefs | +340 |
| Philadelphia Eagles | +400 |
| Baltimore Ravens | +460 |
| Buffalo Bills | +540 |
| Los Angeles Rams | +1800 |
| Washington Commanders | +2800 |
| Houston Texans | +5000 |
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