In a high-stakes matchup for NFL Week 16, the Patriots vs Bills pick is set to be one of the most exciting games of the season, as the New England Patriots (10-3) take on the Buffalo Bills (11-2) at Lincoln Financial Field on Sunday, December 15, 2024. With both teams sitting atop their respective divisions, this game has major playoff implications, making it a must-watch for fans and bettors alike.
Betting Patriots vs Bills Pick for the 2024 NFL Week 16
AFC East Showdown: Patriots vs. Bills – Who Will Dominate?
2024 NFL Season | 104th season of National League in the United States
Week 16: Thursday, December 19th – Monday, December 23rd, 2024
Betting 2024 New England Patriots at Buffalo Bills Week 16 Game
In a key AFC East showdown, the New England Patriots visit the Buffalo Bills in Week 16 of the NFL season.
This matchup has significant playoff implications for both teams, especially for Buffalo, who are battling for the top seed in the AFC.
With the game set for Sunday, December 22, 2024, at Highmark Stadium, fans can expect a heated contest between two teams with much at stake.
The Bills are heavily favored at home, but the Patriots, despite their struggles, are looking to play spoiler.
Buffalo enters the game with an 11-3 record and sits atop the division.
They have one of the league’s best offenses, averaging 31.8 points per game, and are led by MVP candidate Josh Allen.
Meanwhile, the Patriots have endured a tough season, sitting at 3-11, but they have shown some competitiveness in recent weeks.
This game represents an opportunity for New England to disrupt Buffalo’s path to a first-round bye while potentially building momentum for next season.
NFL Week 16 Showdown: New England Patriots (3-11) at Buffalo Bills (11-3)
Sunday, December 22nd, 2024 at 4:25 PM EST FOX | Highmark Stadium, Orchard Park, NY
ATS Odds: Buffalo -14
Money line Odds: Patriots +690, Bills -1205
Over/Under Odds: 46.5
Writer’s Pick for the Patriots vs Bills Game Starting Sunday’s Round of Afternoon Action
Playoff Implications
The Bills are in a heated race with the Kansas City Chiefs for the AFC’s No. 1 seed and a coveted first-round bye.
A win against New England keeps them in contention, but a loss could put their chances in jeopardy.
Buffalo’s high-scoring offense has been their calling card all season, but their defense has had moments of inconsistency, which New England may try to exploit.
For the Patriots, there are no playoff hopes on the line, but pride and player development remain critical.
Quarterback Drake Maye, in his rookie season, has shown glimpses of potential but will face a tough test against Buffalo’s defense.
New England’s focus will be on evaluating talent and building for next year, making this game an important measuring stick against one of the league’s best teams.
Betting New England Patriots Lines to Win
The Patriots have had a challenging season, but they’ve shown grit in several games.
Rookie quarterback Drake Maye has thrown for 2,707 yards and 15 touchdowns this season, though turnovers have been an issue with 10 interceptions.
Maye will rely on weapons like wide receivers DeMario Douglas and Kendrick Bourne, who have combined for over 1,000 receiving yards this season.
Tight end Hunter Henry has also been a reliable target, contributing five touchdowns.
New England’s rushing attack is led by Rhamondre Stevenson, who has rushed for 869 yards and six touchdowns.
The Patriots’ offensive line will need to step up to give Maye time in the pocket and create running lanes for Stevenson.
Defensively, New England has struggled, ranking 30th in total yards allowed.
However, edge rusher Matthew Judon remains a bright spot with seven sacks on the season.
To have a chance, the Patriots will need to force turnovers and capitalize on Buffalo’s mistakes.
Betting Buffalo Bills Lines to Win
Buffalo comes into the game as one of the hottest teams in the league.
Quarterback Josh Allen continues to dominate, throwing for 3,395 yards and 25 touchdowns while adding 11 rushing scores.
His dual-threat ability has made the Bills’ offense one of the most dangerous in the NFL.
Running back James Cook has also been effective, rushing for over 1,000 yards and 14 touchdowns, giving Buffalo a balanced attack.
The Bills’ defense, while solid overall, has shown vulnerability in recent weeks.
They allow 345.5 yards per game and have struggled against the pass, ranking 25th in passing yards allowed.
However, edge rusher Greg Rousseau and linebacker Matt Milano provide a strong defensive presence.
The secondary, led by cornerback Christian Benford, will look to shut down New England’s passing game and create turnovers to give Allen and the offense more opportunities.
Next NFL Games to Follow
Following this matchup, Buffalo will face the Los Angeles Chargers in Week 17, a game that could further impact their playoff seeding.
They’ll then close the regular season with a critical rematch against the Patriots in Week 18.
For New England, their remaining schedule includes a home game against the Chargers and the aforementioned trip to Buffalo.
These games will provide additional opportunities to evaluate young talent and build toward the 2025 season.
Bills vs. Patriots Pick and Score Prediction
Buffalo’s offense is likely to overpower New England in this matchup.
The Bills have too many weapons and a quarterback in Josh Allen who can exploit the Patriots’ defensive weaknesses.
While the Patriots’ offense has shown improvement, their inability to protect the ball and finish drives will make it difficult to keep pace with Buffalo’s high-powered attack.
Score Prediction: Buffalo 34, New England 17
NFL ATS Pick: Buffalo -14
NFL Total Pick: Over 46.5
Bet the NFL Week 16 Games | NFL Live Betting MyBookie Betting Lines for the Tournament
^ TopNew England at Buffalo Betting Trends Today
- Bills are 9-5 against the spread this season.
- Patriots are 5-8-1 against the spread this season.
- Patriots are 2-7 straight up in Drake Maye’s starts this season.
- Bills are 4-2 ATS as home favorites in the 2024 season.
- Patriots are 3-4 ATS as road dogs in the 2024 season.
- OVER is 9-5 in the 14 games for both teams in 2024.
Bills vs. Patriots Series History
Last meeting:
Patriots 21, Bills 27: December 31, 2023: Week 17 – Highmark Stadium, Orchard Park, NY
Head-to-head (includes postseason games):
New England Patriots lead series 78-50-1
^ TopThe #Bills are debuting a new uniform this week vs the #Patriots. pic.twitter.com/Sd7GWJKRLj
— New England Sports Fellow (@NESportsFellow) December 17, 2024
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2023 Patriots vs Bills Odds and Betting Pick for this NFL Week 17 Matchup
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AFC East rivals New England and Buffalo throw down on the Bills’ field in an early Sunday matchup that has implications for Buffalo’s playoff hopes. The Bills are on fire after winning 4-of-5 and 3 straight. New England wants to play spoiler.
Can Buffalo cover a massive spread that has floated to -12? Will the Patriots scare the rival Bills?
MyBookie offers the NFL betting odds, game analysis, and betting pick for the New England Patriots versus the Buffalo Bills which are playing on Week 17 of the NFL season.
2023 Patriots vs Bills Odds and Betting Pick for this Week 17 Matchup | MyBookie NFL Regular Season Preview
New England Patriots vs Buffalo Bills | NFL Week 17
ATS Odds: Bills -12
Money line Odds: New England Patriots Line: +500 / Buffalo Bills Line: -725
Over/Under Odds:40.5
Sunday, December 31st, 2023 at 1:00 pm ET | CBS
Highmark Stadium, Orchard Park, New York
Why Bet on Patriots versus Bills
New England remains one of the worst teams in the NFL, but the Patriots have shown signs of stepping it up in recent games. The Pats played terrific football when upsetting the Denver Broncos in their last.
New England’s defense is a well-coached and solid unit. The offense is more effective with Baily Zappe in charge than Mac Jones. New England has won 2-of-3 over the Steelers and the Broncos and played Kansas City tough until late in a 27-17 loss.
Why Bet on Bills versus Patriots
Buffalo is on fire. The Bills not only are on a 3-game winning streak, but the victories came against 3 squads with tough defenses, the Chiefs, the Cowboys, and the Chargers.
The Bills scored 31 points against Dallas’ defense in their last home game. Josh Allen and his mates know what’s at stake on Sunday. So we should expect Buffalo to play their best football.
Buffalo versus New England Final Betting Prediction
The Bills will beat the rival Patriots but asking Buffalo to win by more than 10 points is a tall ask. Buffalo has played at such a prominent level that a bounce, ala the 49rs versus the Ravens in NFL Week 16, is a possibility.
The difference is that the Ravens are one of the best teams in the NFL, which is why Baltimore beat San Francisco. New England isn’t a good football team. So Buffalo gets the victory. However, the final score is going to be much closer than many Bills fans believe. Back New England to score the ATS win.
2023 NFL Pick: ATS New England Patriots +12 | Bet Patriots vs Bills
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How to Bet Patriots at Bills NFL Odds & TV Info
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How to Bet Patriots at Bills NFL Odds & TV Info
- When: Saturday, 8:15 PM ET
- Where: Highmark Stadium
- TV: CBS
- Stream Option: Paramount+
- Opening NFL Lines: Bills -4 (total 44)
For just the second time ever, the rival New England Patriots and Buffalo Bills will meet in the postseason as they square off in a Wild-Card game Saturday night from what is going to be an extremely cold Buffalo with the Bills favored on the NFL betting lines.
Season Series
In Week 13, the Patriots won in Buffalo 14-10 on a Monday night in extremely bad conditions with snow and heavy winds. New England QB Mac Jones completed just two of three pass attempts for 19 yards. Damien Harris scored on a 64-yard run in an outing the Patriots out-gained Buffalo 222 to 99 in yards rushing. Buffalo had just 230 yards offense. Tyler Bass missed a 34-yard attempt wide right into the wind in a game the Bills managed 10 points on four drives inside the New England’s 20.
In Week 16 at New England, the Bills won 33-21 as Josh Allen threw for three scores and cornerback Micah Hyde made two interceptions. The Bills never trailed and had no punts or turnovers. Jones was 14 of 32 passing for 145 yards and two interceptions.
Why Bet on New England?
The Patriots lost for the third time in four games Sunday, 33-24, but New England wouldn’t have won the AFC East even with a win because Buffalo won. The Patriots have played in wild-card games before under Bill Belichick — but had never been to the playoffs in the Belichick era as a wild card. All 17 of the previous playoff appearances in his years there have come after a division title.
Rookie QB Mac Jones completed 20-of-30 passes for 261 yards, a touchdown and an interception. Jones was pick-sixed on his first throw of the game. Dolphins cornerback Xavien Howard read Jones looking for a shallow completion on third down and jumped the pass. After that dreadful play, Jones had a solid night. In the Patriots’ seven-game win streak, Jones threw nine touchdown passes and two interceptions. In the four games since, he has six touchdown passes, five interceptions and a costly lost fumble.
Jones became the first rookie quarterback to lead his team to the playoffs since Dak Prescott in 2016. Jones led all rookies this season in completion percentage (67.6), passing yards (3,801), touchdown passes (22) and passer rating (92.5). He is bidding to become just the fourth rookie quarterback since 2000 and first since Russell Wilson in 2012 to go on the road and win his first NFL postseason start.
The Patriots ranked second in the league with 24 rushing touchdowns this season, including 15 rushing touchdowns from running back Damien Harris, tied for the second-most in the NFL this season. Harris is listed as questionable for this game but expected to play.
New England placed cornerback Jalen Mills on the reserve/COVID list on Tuesday. This doesn’t officially rule him out of Saturday’s game, but it does open the possibility that the team could be without their starter opposite J.C. Jackson. Third-year CB Joejuan Williams would be one candidate to step in if Mills is out
Jackson led the NFL with a career-high 23 passes defensed, including eight interceptions. Jackson, who has 25 career interceptions, became the fourth player in the Super Bowl era to record 25-or-more interceptions in his first four seasons.
Saturday’s game marks the seventh time in team history that the Patriots will play a division foe in the postseason and the first time since the 2010 season. The Patriots are 5-1 in those games.
Why Bet on Buffalo?
The Bills won the AFC East with a 27-10 victory over the Jets on Sunday, Buffalo’s fourth straight win. The defense limited the Jets to a franchise-low 53 yards of total offense, and Cam Lewis even blocked a punt. Buffalo’s defense led the way by setting a franchise record in limiting New York to generating four first downs and sacking rookie Zach Wilson nine times, the most by Buffalo since getting 10 in a 23-0 win over Commanders on Oct. 20, 2011.
Josh Allen completed 24-of-45 passes for 239 yards and two touchdowns, rushing five times for 63 yards. Allen became the first player in franchise history to pass for 4,000 yards in consecutive seasons. With six rushing touchdowns this season, he also became the first quarterback ever with six-or-more rushing touchdowns in each of his first four seasons.
Stefon Diggs caught 9-of-14 targets for 81 yards and a touchdown. Diggs actually opened the game with a 10-yard touchdown on Buffalo’s first drive. Diggs’ 14 targets tied Gabriel Davis’ total for the team lead, seeing 13 targets for the third time in his last five games. Diggs is one of two NFL players with 1,000-or-more receiving yards and at least six touchdown catches in each of the past four seasons, joining Mike Evans.
Fellow WR Emmanuel Sanders (knee) does not have an injury designation for Sunday’s game. He has practiced in full after sitting out Weeks 17-18. He finished the regular season with 42 receptions, 626 yards and four touchdowns while starting 13 of 14 games in 2021.
Devin Singletary rushed 19 times for 88 yards and one score, hauling in both of his targets for 24 yards and a receiving touchdown in Buffalo win over the Jets. Buffalo’s run game has found traction and been productive with the second-most rushing yards in the league (636) and the seventh highest yards per carry average over the final month of the season (4.82).
Sean McDermott has led the Bills to playoff appearances in four of his five seasons as an NFL head coach, including consecutive AFC East titles, the team’s first division crowns since 1995. His 2021 club was the only team in the NFL to finish in the top five in both total offense (381.9 yards per game, fifth) and total defense (272.8 yards allowed per game, first).
Along with the Dallas Cowboys, Buffalo is one of just two teams to finish among the top six in schedule-adjusted EPA on both offense and defense.
Expert Prediction
Bills 23, Patriots 16
