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The Tennessee Titans have jumped out to a lead in the AFC South race, with the Indianapolis Colts sitting in second place. This week, the Colts will look to pull closer to the Titans in the division standings, as they host Tennessee in a key division matchup. While the Titans have built major momentum over the last few weeks, the progress the Colts have been making should not be overlooked going into this contest.

Let’s take a look at the upcoming match between the Tennessee Titans vs Indianapolis Colts so you can bet against their NFL odds.

NFL Betting Preview for Titans vs. Colts

Tennessee Titans

There aren’t many two-week stretches in the NFL that are better than the two weeks assembled by the Tennessee Titans. They have beaten two Super Bowl contenders in two weeks, taking down the Buffalo Bills and Kansas City Chiefs back to back, beating Kansas City 27-3 last week. But the Titans must be careful to avoid a letdown this week, as they head back on the road against an opponent they have already defeated this year.

For the Titans, their defense will be just as important as their offense coming into this matchup. While Tennessee’s offense generates plenty of attention due to weapons like Derrick Henry and AJ Brown, Indianapolis has found some offense over the last few weeks as well. The Titans will need to guard against the deep ball, which has become a recent staple of the Colts offense and could tilt the scales in the favor of Indianapolis.

Indianapolis Colts

The Indianapolis Colts are coming off of a big win of their own last week, having defeated the San Francisco 49ers on the road on Sunday Night Football. In a rain-soaked game full of turnovers, the Colts executed better than the Niners in the second half and pulled away late. And the Colts continued to have success throwing the ball downfield, putting the game away with a deep touchdown pass from Carson Wentz.

Against the Tennessee Titans, the top priority always has to be playing stout defense. But the Colts will need to remain aggressive offensively if they are going to take advantage of their chance to pull closer in the AFC South race. The connection between Wentz and Michael Pittman in the passing game has improved dramatically over the last few weeks and is worth keeping an eye on here.

Titans vs. Colts Pick: Colts -3

The betting line for this game has moved significantly in the favor of the Colts, as Indianapolis opened as an underdog before becoming a three-point favorite. That kind of line movement signifies the confidence that bettors have in the Colts this week, in spite of the momentum the Titans have built. Both teams enter at 5-2 against the spread on the season, with the Colts being equal to the Titans in that regard.

Both of these teams have shown that they can score in bunches in most weeks, making offensive execution the key to this game. But the Indianapolis Colts are the best play to make in this matchup, as they are not facing the letdown spot that the Titans are after picking up two massive victories at home.

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