Top ATS Picks for the Top Games NFL Week 6: Expert Bets to Watch

Vegas NFL odds are the betting lines set by sportsbooks in Las Vegas for NFL games.

These odds typically include:

• Moneyline:
  The odds on which team is expected to win the game outright.
• Point spread:
  The number of points by which a favorite is expected to win or an underdog is expected to lose.
• Over/under:
  The total number of points expected to be scored in the game.

Vegas odds are often considered to be among the most accurate in the industry, as they are set by experienced oddsmakers like MyBookie who have access to a wealth of data and information.

To find the latest Vegas NFL odds, visit our NFL News section.

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We roll along to the National Football League Week 6 slate. The week starts with the Thursday Night Football game in Kansas City. That will be one of our picks for the week.

Let’s take a look at the NFL Week 6 Against the Spread Picks.

2023 NFL Week 6 ATS Picks | MyBookie Regular Season Preview

2023-24 NFL | 104th season of the National Football League
NFL Week 6: Thursday, October 11th – Monday, October 17th, 2023

Denver Broncos at Kansas City Chiefs

ATS: Chiefs 10.5
Thursday, October 12th, 2023 at 8:15 PM | PRIME VIDEO
GEHA Field at Arrowhead Stadium, Kansas City, MO

One of the best rivalries in the National Football League. The Broncos are struggling, with a 1-4 start, while the Chiefs have won four straight games. The Broncos are the worst defensive team in the National Football League and are coming off a loss to the Jets.

Patrick Mahomes was not great in his last prime-time game, as the Jets competed from start to finish. Look for the short week to keep this game competitive.

The offenses start slow, and in the end, the best quarterback on the field helps his team win their fifth straight. But, it stays under the spread. Betting the Denver Broncos to cover is our choice.

NFL Week 6 SNF Pick: Broncos +10.5 | Bet oncos at Chiefs
MyBookie Betting Lines for the Game

Tennessee Titans vs. Baltimore Ravens

ATS: Ravens -3.5
Sunday, October 15th, 2023 at 9:30 AM | FOX
Tottenham Hotspur Stadium, London

The London series sees its third straight game. The Jaguars won the first two. Now their divisional foe – the Tennessee Titans, get their turn over there. It’s Derrick Henry and his running attack against Lamar Jackson.

Jackson and the Ravens are coming off a terrible loss last week to the Steelers in a game they led most of the way. Baltimore needs to get back on track in a competitive AFC North.

For the Titans, they are coming off a home loss. For a team that does not allow a ton of running yards, Zack Moss went nuts on them last week.

Look for the long flight to slow these guys down a bit, and the Ravens have trouble scoring. Look for the Titans to cover this game.

NFL Week 6 ATS Pick: 49ers -4.5 | Bet itans vs. Ravens
MyBookie Betting Lines for the Game

San Francisco 49ers at Cleveland Browns

ATS: 49ers -4.5
Sunday, October 15th, 2023 at 1:00 PM | NFL NET
Cleveland Browns Stadium, Cleveland, OH

After watching Sunday Night Football, how do you not pick the San Francisco 49ers? The spread seems like a trap. Sure, the game is in Cleveland, but what have the Browns done to give them a chance to compete in this game?

The Browns’ defense is one of the best in the league, but no team has shown the ability to slow down Brock Purdy and the San Francisco offense.

We are going to go ahead and take the best team here and taking San Francisco on the road.

NFL Week 6 ATS Pick: 49ers -4.5 | Bet 49ers
MyBookie Betting Lines for the Game

Miami Dolphins over Carolina Panthers

ATS: Dolphins -14
Sunday, October 15th, 2023 at 1:00 PM | CBS
Hard Rock Stadium, Miami Gardens, FL

This could be the best team in the NFL against the worst team in the NFL. So, the Dolphins have a loss, but they still have shown to be one of the best offenses in the league.

Josh McDaniel has tons of weapons. The Panthers tried to slow down the Detroit offense and could not do that.

Look for Miami to score, score, and score more and blow away the Panthers in this game. Take the Dolphins.

NFL Week 6 ATS Pick: Dolphins -14 | Bet Dolphins over Panther
MyBookie Betting Lines for the Game

Chicago Bears over Minnesota Vikings

ATS: Vikings -3
Sunday, October 15th, 2023 at 1:00 PM | FOX
Soldier Field, Chicago, IL

The Bears are coming off a win and seem to look better. The Vikings look snake-bitten and will likely not have Justin Jefferson in this game.

Look for an upset in the making here, as the Bears beat the Vikings on Sunday. The winner of this game will move out of last place in the NFC North.

NFL Week 6 ATS Pick: Bears +3 | Bet Bears over Vikings
MyBookie Betting Lines for the Game

Buffalo Bills over New York Giants| Sunday Night Football

ATS: Bills -15
Sunday, October 15th, 2023 at 8:20 PM | NBC
Highmark Stadium, Orchard Park, NY

How will the Giants compete in this game when they have not been able to compete pretty much all season so far?

The Giants only have one win, which was a come-from-behind win over Arizona in the game’s final seconds.

Buffalo is coming off a loss, and there is no doubt Josh Allen will want to put that behind him and get back on track. The Bills win this game big.

NFL Week 6 SNF ATS Pick: Bills -15 | Bet Bills over Giants
MyBookie Betting Lines for the Game

The following NFL betting odds are based on MyBookie Sportsbook.

There you go. Those are our favorite games for Week 6 of the National Football League to bet!

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MyBookie Odds for the Games

Previous Betting News

Since the start of the season, we have spoken regularly about the current level of parity in the NFL, and how it makes predicting games that much tougher. A perfect example of this could be seen in Week 5, where we had 10 games decided by 7 points or less. Looking ahead to Week 6, we see a lot of the spreads sitting very much in that range, and while it certainly makes things more challenging, that is all part of the fun of wagering on the NFL. We are ahead of the game with our ATS picks for the season, going 8-4 to this point, as well as putting together a 24-12 record with all our selections combined. It’s about time for a perfect week, so let’s see of we can manage that with our ATS picks for Week 6 of the NFL season. Let’s get right to it so you can bet against the NFL Odds.

Week 6 Against The Spread Betting Picks | 2022 National Football League Odds

Cincinnati Bengals (-1 ½) at New Orleans Saints

Making it to the Super Bowl is no guarantee of success the following season, which is what we are seeing with the two teams who went to the championship game last season. The Bengals, who lost to the Rams in the SB, are sitting at 2-3 on the season, but are still very much in the hunt in the AFC North at the moment. That said, they need to start stringing together some wins if they are to make it to the playoffs and go on another run. This weekend is certainly not an easy road trip for them, as New Orleans is never a pleasant place to play for visitors. The Bengals, though, have been a great road pick, going 7-1 ATS in their last 8 games away from home.

Dallas Cowboys (+4 ½) at Philadelphia Eagles

One of the games of the week is an NFC East matchup that will see the winner land on top of the division. The Eagles are there right now, courtesy of being the only team in the NFL with an unbeaten record, but the Cowboys, as well as the Giants, are hot on their tail. The Cowboys have bounced back nicely from a Week 1 loss and losing their QB to reel off 4 in a row. There is talk that Dak Prescott might be back for this one, so keep an eye on the spread if that is indeed announced. Prescott or not, I still like the Cowboys to cover as a road dog here, as they have covered in 10 of their last 11 games played away from home.

Carolina Panthers at LA Rams (-11)

We are just 5 weeks into the season, but we already have out first coaching casualty, with the Panthers deciding to part ways with Matt Rhule. While the Panthers have just 1 win on the season, you have to feel some sympathy for Rhule, as his team has been hit with the injury bug, with Baker Mayfield the latest to go down. Sometimes, we will see a team get a nice bounce after a coach is fired, but I don’t think we will see that this weekend. The Rams have been struggling, but this feels like the kind of matchup where they can put right some wrongs. The Panthers are just 3-7 ATS in their last 10 road games.

I have read enough, I need to place my bet now. What to do?

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MyBookie Betting Lines for the bout

Previous Betting News

Prior to the start of every NFL season, we all have our own ideas about which teams will contend for the Super Bowl and which are destined to be cellar dwellers. There are also a handful of teams that we would suggest as potential dark horse picks. For the most part, things are playing out somewhat as expected, although if you had said that the Arizona Cardinals would be the only unbeaten team and the Chiefs would be last in their division aster 5 weeks, you might have been considered a little crazy. That is where we are though, but things can change quickly in this league. As we look ahead to Week 6, we have put ATS picks lined up as we look to break out of a mediocre start to our NFL Betting picks this season.

Week 6 ATS Picks for the 2021 Season | NFL Betting

Cincinnati Bengals (-3 ½) at Detroit Lions

You would have to say that the Bengals are among the teams that should be classified as a bit of a surprise this season. They are 3-2 right now and perhaps a little unlucky not to be 4-1 after an OT loss to the Green Bay Packers in Week 5. This weekend, they will be on the road to face a Detroit Lions team that is yet to win and who seem to be finding incredible new ways to lose every week. The Bengals appear to be a team on the rise and have had some real success versus the Lions, winning 6 in a row and covering the spread in 5 of those wins. They are also 5-0 ATS in their last 5 visits to Detroit, so a lot to like here.

Green Bay Packers (-4 ½) at Chicago Bears

It is still very early in the season and a lot can change, but it already looks as though the Green Bay Packers are well on course to win the NFC North. They can certainly take a firm grasp of the division with a win on the road against Chicago this weekend. This is easier said than done, as Chicago have moved to 3-2 on the season despite not seemingly having a clear idea of who their starting QB is this season. The Packers have absolutely dominated this matchup in recent seasons, winning 10 of their last 11 against the Bears. They are 4-1 ATS in their last 5 games overall and will face a Bears team that has covered just 3 times in their last 10 against divisional opponents.

Dallas Cowboys (-4) at New England Patriots

When you look at the teams sitting atop their respective divisions at the moment, you are generally looking at teams who have a proven starting QB under center. The Dallas Cowboys are 4-1 and dominating in the NFC East with Dak Prescott looking very much as though he has truly recovered from the injury that derailed his 2020 season. The Patriots haver a good young prospect in Mac Jones, but it also looks like they need help in many other areas outside of QB. The Cowboys have covered in all 5 of their games this season, while the Patriots are 3-6 ATS in their last 9 overall. The Cowboys are hot right now and I like them to win and cover.

I have read enough, I need to place my bet now. What to do?

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MyBookie Betting Lines for the Game

Previous Betting News

Week 5 of the NFL season will come to a close on Monday night after the Washington Redskins and New Orleans Saints lock horns. It’s never to early to look ahead to Week 6 Odds, especially with so many big games on the Week 6 docket. As we do every week, we are going to take a closer look at these games to see if we can identify some picks that might help boost your bankroll. We are going to go with ATS picks with this article, but we will also have SU and O/U picks, as well as a few parlay tickets for you guys. Keep an eye out for those other articles, which will be up today. For now. Let’s get to some ATS predictions for Week 6.

NFL Week 6 ATS Betting Picks

Philadelphia Eagles (-3) at New York Giants

The Defending Super Bowl Champions are off to a low 2-3 start to the season and have now lost in back to back weeks, both times as a favorite in the 3-point range. It’s not all doom and gloom just yet, though, as the NFC East is still wide open and will get even tighter if the Redskins fall to the Saints on Monday night.

This looks like a match-up that could help get the Eagles back on track, as they have won 7 of their last 8 meetings with the Giants. They are 9-2 SU in their last 11 on the road to the Giants, and they are also 8-3 ATS in those games. I like the Eagles to win and cover here.

Pittsburgh Steelers (+2 ½) at Cincinnati Bengals

A few of the preseason favorites in the NFL have got off to slow starts, with the Pittsburgh Steelers certainly falling into that category. They delivered a massive performance at home in Week 5, though, dumping the Atlanta Falcons 41-17. They still have some ground to make up on the AFC North leading Bengals, but they will have a shot at reducing that gap on the road this weekend.

Cincinnati has been one of the surprises of the season, stretching their season record to 4-1 with a win over the Dolphins last Sunday. The Steelers have been good against Cincinnati on the road, going 11-3-1 ATS in their last 15 visits there. I like Pittsburgh to cover as the underdog.

Chicago Bears (-1 ½) at Miami Dolphins

After a bright start to the season, the Dolphins have been brought back to earth with back to back losses over the last couple of weeks. They have now given up the lead in the AFC East and are looking more like the team that we expected to see. They will be back home this Sunday, but they will be up against a hot Chicago Bears team that is off to a solid 3-1 start.

The Bears offense has been good, but they have perhaps been even better defensively, giving up just 16 PPG through their first 4 games. Overall, the Bears are 5-1 ATS in their last 6 and seem like a good bet to cover here.

San Francisco 49ers at Green Bay Packers (-7 ½)

A season that began with so much promise for the 49ers has gone sour very quickly, with the loss of Jimmy Garoppolo for the season being just one of the problems that San Francisco have to deal with.

They are 1-4 on the season and have a Monday night stop in Green Bay in Week 6, a place where they have struggled mightily, winning just twice in their last 10 visits there. They are just 1-3-2 ATS in their last 6 games at Lambeau, and while the Packers are not playing well right now, I still like them to cover here.

Previous Betting News

With the start of the 2016 NFL regular season quickly approaching, you’re going to find that the early NFL betting predictions you’re about to get on every game on the Week 6 docket, simply salivating! Let’s rock and roll!

Let’s Take a Look at the 2016 Week 6 ATS Betting Picks

Thursday, October 13, 2016

Broncos at San Diego Chargers (+3)

After losing to Denver twice last season, but covering the spread as a 10-point underdog in their road date against the Broncos, I say Philip Rivers and the Bolts get a small measure of payback by getting the home win over Denver in this Week 6 AFC West divisional clash.

Sunday, October 16, 2016

San Francisco 49ers at Buffalo Bills (-7)

The Bills have an aggressive defense and solid offense, but the Niners are the pick for me, to a least keep it close on the road against a Rex Ryan Bills team that often underachieves when you least expect it.

Philadelphia Eagles at Washington Redskins (-3)

The Skins have won three straight against Philly while covering the spread in four straight. I’m not real high on Washington heading into 2016, but I like the Redskins to win and cover over the rebuilding Birds and their first-year head coach Doug Pederson.

Cleveland Browns at Tennessee Titans (-3.5)

I love Browns head coach Hue Jackson more than Tennessee’s Mike Mularkey and still believe that RG3 can be a franchise quarterback. The Browns cover the spread in a thriller!

Baltimore Ravens at New York Giants (-3)

I don’t think there’s gong to b much defense played in this Week 6 affair. The edge – and ATS cover – goes to Eli Manning and the G-Men at home.

Carolina Panthers at New Orleans Saints (+4.5)

The Panthers ad Saints can both light up the scoreboard but only one team lays any sort of competent defense in this affair and it’s not New Orleans. Cam Newton and company get the SU win an accompanying ATS cover.

Jacksonville Jaguars at Chicago Bears (-3.5)

John Fox will make sure that Jay Cutler and the rest of his Chicago Bears know this is a game they can’t afford to lose against an inferior opponent and that’s the only reason Chicago covers the NFL betting line!

Los Angeles Rams at Detroit Lions (-1.5)

Not many folks are talking about Matthew Stafford and the Lions, but I believe they could surprise in a big way in 2016. Detroit wins and covers the NFL betting line with room to spare!

Pittsburgh Steelers at Miami Dolphins (+3.5)

Maybe it’s me, but I think Pittsburgh’s Ben Roethlisberger could throw a football left- handed better than Miami’s Ryan Tannehill ever could with his dominant hand. Pittsburgh wins and covers the spread going away.

Cincinnati Bengals at New England Patriots (-4)

With Week 6 representing the second game that Tom Brady will play in 2016, I expect the Patriots to be firing on all cylinders. New England wins while sending a message to the Bengals and every other AFC title contender.

Kansas City Chiefs at Oakland Raiders (PK)

The Chiefs have won three straight over the Raiders and five of the last six meetings overall, but I’m going with Oakland to snap that skid by getting the narrow home win as a pick ‘em.

Atlanta Falcons at Seattle Seahawks (-10)

The Seahawks get the home win in this Week 6 NFC clash, but I think the double-digit point spread is just a tad too high for Russell Wilson and company to cover. Atlanta covers in a losing effort.

Dallas Cowboys at Green Bay Packers (-6)

The Packers have won five straight over the Cowboys while going 4-1 ATS along the way. I say Aaron Rodgers and company will make it six straight while narrowly covering the NFL betting line.

Indianapolis Colts at Houston Texans (-1.5)

While I’m expecting the Indianapolis Colts to bounce back in a big way with Andrew Luck back under center, the Houston Texans are my pick to bring home the bacon in this Week 6 AFC South divisional showdown mostly because they have the far better defense.

Monday, October 17, 2016

New York Jets at Arizona Cardinals (-4)

The Jets have an elite defense, but so does Arizona. When it comes to offense, the Cardinals are far and away the superior team. Carson Palmer and company cover with room to spare!

Previous Betting News

In line with our series of articles on the best NFL ATS picks for the upcoming season, let’s take a look at our predictions for the sure 2016 winners against the spread.

Sure ATS Betting Lines For NFL Week 6

Denver Broncos (-3) at San Diego Chargers

Week 6 NFL ATS Pick: Broncos (-3)

There is a general consensus across the league that the Chargers will be a slightly improved team while the Denver Broncos will take a step back from their 2015 Super Bowl-winning campaign. In many ways, the offseason changes made by the two teams sort-of explain such expectations. But then again, I’d really be wary about trusting San Diego for the win or even the points in this game, given that Denver has pretty much owned them in recent years. Per the record books, Denver is flawlessly 5-0 in its last five trips to San Diego and is impressively 9-1 in its last 10 overall meetings against the Chargers. So, even with the concerns about Denver’s quarterback situation, there still looks to be a lot of value for the Broncos in this game, as per the betting trends. Plus, the QB situation in Denver last year was far from perfect, yet Denver finished the season with the best AFC record in the regular season, before outwitting better-endowed offensive teams to eventually claim the Super Bowl. Doing the same against the offense-reliant Chargers and covering the standard 3-point spread should thus be within very strong realms of possibility for this well-coached and extremely disciplined Denver team.

Cincinnati Bengals at New England Patriots (-4)

Week 6 NFL ATS Pick: Patriots (-4)

Try as you may, it’s really hard to argue against a New England team that has been playing the best football in the franchise history over the past decade, with several divisional, conference and national titles to show for their dominance. One of the teams that have been on the end of a tough run of results against the Pats is Cincinnati, who are winless against New England in Foxboro since 1986. The Patriots have are also 8-2 in their last 10 overall games against the Bengals, including wins of 7-or-more points for New England in each of their last three straight meetings at Foxboro. Add to the fact that Cincy has lost a couple of key talents in this offseason; I’d expect nothing other than another win plus the points for the home-favored Patriots.

Carolina Panthers (-4.5) at New Orleans Saints

Week 6 NFL ATS Pick: Saints (+4)

After blistering their way to 15-1 season and a solid 11-5 ATS mark, including a two-game sweep over the Saints, it appears as if the Panthers should be the obvious pick in this divisional fixture. That said, the Saints lost by just three points when they played Carolina at home and by just five points in the return fixture at the Bank of America Stadium. That was, of course, when New Orleans had one of the worst defensive units in the NFL. With a better D in 2015 and Drew Brees doing his thing to matchup Cam Newton and gang offensively, the value here should be with the Saints, who’ve actually been one of the better home teams in the NFC South division.

Previous Betting News

The incendiary Arizona Cardinals will beat the San Francisco 49ers when the two teams square off in their NFC West division matchup on Sunday, making the only ‘real’ question surrounding this contest whether or not the Cards will cover the NFL betting spread as double-digit road faves.

Let’s find out now!

Arizona at San Francisco NFL Betting Game Preview

When: 4:05 PM ET, Sunday, November 29, 2015

Where: Levi’s Stadium, Santa Clara, California

NFL Odds: Cardinals -10.5 O/U: 44.5

Betting on the Arizona Cardinals (8-2 SU, 6-4 ATS)

The Cards have won four straight games including their thrilling 34-31 win over Cincinnati in Week 11 as a 4-point home favorite.

Veteran quarterback Carson Palmer completed 20 of 31 passes for 317 yards with four touchdowns to lead the Cards to the narrow victory. Palmer also overcame two interceptions to get the win, but head coach Bruce Arians wasn’t very happy afterward.

“It’s kind of sounding like a broken record, but I really didn’t like the way we played,” Arians told reporters.

“We had another tough opponent in the Bengals with only one loss but we were able to drive down late in the game and finish it off,” safety Rashad Johnson said. “We’re finding ways to win, and we have momentum at the perfect time.”

The 12-year veteran has tossed 11 TD passes in his past three games to take over the league lead with 27 and just three short of Kurt Warner’s single-season franchise mark of 30 TD passes set in 2008.

“He can have rough moments, shake them off and just come on back,” coach Bruce Arians said. “He’s like a really good pitcher who can’t find the plate, then all of a sudden he gets in a groove.”

Now the Cards are set to face a new starting quarterback for Frisco with veteran Blaine Gabbert replacing former starter Colin Kaepernick two weeks ago.

Arizona (8-2) blew the Niners out of the water in their first meeting this season while intercepting Kaepernick four times and returning two for touchdowns in the Cardinals’ 47-7 win. Still, the Cards are wary.

“Gabbert is taking care of the football better. The receivers are more involved so it’s a good challenge for us,” said Arizona safety Tyrann Mathieu, who scored one of those first-quarter touchdowns in September.

“It seems like Gabbert has a better understanding of coverages and getting his receivers involved. He’s an underrated passer. We know those guys are going to come out fired up, ready to prove a point.”

“They’re still the Niners. It would mean a lot to this franchise,” linebacker Kevin Minter said. “We’ve just got to get it done. It’s not going to be an easy game by any means. … It would be a big step forward for this organization as far as being on top of these guys. It’s time for us to finally be on top.”

Betting on the San Francisco 49ers (3-7 SU, 4-6 ATS)

Say what you like, but I say Blaine Gabbert is an improvement over former starter Colin Kaepernick. Gabbert played good football by completing 22 of 34 passes for 264 yards and one touchdown in Frisco’s 29-13 Week 11 loss against Seattle as a 14-point road underdog.

Unfortunately, the Niners allowed Seattle rookie running back Thomas Rawls to rush for a whopping 209 yards in the loss as defensive lineman Glenn Dorsey tore his right ACL on the Seahawks’ first play from scrimmage. The 49ers went on to allow a season-worst 255 yards on the ground.

“When Glenn got hurt, I didn’t like our body language,” coach Jim Tomsula said. “We have to address that.”

Gabbert has never played alongside leading rusher Carlos Hyde, who has been out since Oct. 22 with a stress fracture in his foot.

Cardinals vs 49ers Game Analysis

Arizona is the only team in the league right now ranked inside the top five on offense and defense and it is this excellence on both sides of the ball that I believe will lead them to the emphatic SU win and ATS cover.

Arizona has compiled a near-perfect 12-1 ATS mark in their last 13 road games against a team with a losing home record while also going 13-3 ATS in their last 16 games following an ATS loss and 4-1 ATS in their last five road games.

Conversely, the 49ers are just 3-7 ATS in their last 10 home games and 7-18-1 ATS in their last 26 games against their NFC West division rivals.

While Arizona has been busy compiling a stellar 17-5 ATS mark in their last 22 games against a team with a losing record and 18-7 ATS mark in their last 25 games following an SU win, the 49ers are just 3-8-1 ATS in their last dozen games against their NFC counterparts and just 4-11-1 ATS in their last 16 games overall.

Arizona wins easily to cover the spread!

My Betting Pick