The Buffalo Bills enter the 2024 season with high expectations, aiming to secure their first Super Bowl victory. To help you navigate their challenging schedule and make informed Bills Betting picks, we’ve identified the key matchups that will define their season.
Buffalo Bills Top Games of the Season Odds
Can the Buffalo Bills finally break through and capture a Super Bowl title?
Bills Season | 55th in the National Football League | 8th under head coach Sean McDermott
2023: 11–6 record / 1st AFC East
2024 Buffalo Bills Season
One of this seasons most discussed squads, the Buffalo Bills have high hopes that they can surpass the Miami Dolphins and New York Jets in the deep AFC East.
To do so, someone must step up and support fantastic quarterback Josh Allen.
Will the Bills get it done this season? Check out an analysis of Buffalo’s top games heading into the 2024 NFL Season.
Writer’s Picks for Bufalo Bills Top Games of the Regular Season
NFL Week 2 at Miami Dolphins
Miami and Buffalo played in two intense games in 2023.
The Bills handed Miami their first loss of the season.
But in this contest, Miami is at home.
It’s too early to go against Tua and his mates at Hard Rock Stadium.
Miami scores the victory.
NFL Week 4 at Baltimore Ravens
Buffalo must weather a brutal early season stretch where they play three straight road games versus teams that can win the Super Bowl.
The first is against the Baltimore Ravens.
Allen will have some success.
So will Lamar, though.
It’s tough seeing the Bills winning this game.
Ravens score the W.
NFL Week 5 at Houston Texans
By all account, C.J. Stroud and the Texans are legit Super Bowl contenders.
Stroud looked good in his first preseason game.
Also, the Houston defense appears better than last season.
Buffalo loses their third game in 5 weeks.
NFL Week 6 at New York Jets
Hasson Reddick should be in a Jets uniform by NFL Week 6.
Right now, Reddick is a holdout due to a contract dispute.
If Reddick plays, the Jets will have another player that can counter Allen’s ball carrying ability.
The Jets protect their home field with a win.
NFL Week 9 vs Miami Dolphins
After losing four of their first six games, things won’t be looking good for the Bills heading into the second half of the season.
NFL Week 9 is when Buffalo could turn the switch.
The Bills will get payback in a big way versus the Dolphins in this one.
Buffalo will have their backs against the wall to make the playoffs.
A Bills’ blowout victory is possible.
NFL Week 11 vs Kansas City Chiefs
It’s always tough to go against Kansas City.
But it’s easy to envision Allen and rookie wide receiver Keon Coleman clicking by NFL Week 11.
The Bills have an advantage because this takes place at Orchard Park.
Allen, along with Cincinnati’s Joe Burrow, have a way of beating Patrick Mahomes and the Chiefs.
The Bills get it done.
NFL Week 13 vs San Francisco 49ers
Many expect the 49ers to roll to the Super Bowl this season.
The Niners should be one of the top squads in the NFL.
By NFL Week 13, SF won’t be excited to have to travel all the way across the country to play the Bills in Buffalo.
The Bills will be fired up to prove their season comeback is in full swing.
Buffalo wins another.
NFL Week 14 at Los Angeles Rams
NFL schedulers had it in for Buffalo this season.
The Bills play three of the NFC’s top teams in a row towards the end of the season: the 49ers, the Rams, and the Lions.
The Rams game happens at SoFi.
So Buffalo must travel across the country to face the Rams a week after battling Brock Purdy and the 49ers.
That’s a recipe for a Buffalo loss.
NFL Week 15 at Detroit Lions
We can’t expect the Bills to beat the Detroit Lions at Ford Field.
Detroit should be one of the best teams in the NFL and is a real Lombardi contender.
Also, by NFL Week 15, Buffalo will have tired of playing against top NFC West squads after going against the Niners and Rams.
The Lions score the win.
NFL Week 17 vs New York Jets
Buffalo should beat the Patriots in NFL Week 16 and NFL Week 18.
So the key matchup in the final month of regular season play will be versus the Jets at home.
It’s tough to go against either squad.
The thinking here, though, is that the J-E-T-S, due to their much easier schedule, scores the road win.
Josh Allen tends to tire towards the end of every regular season because so much each season lands on his shoulders.
The same will happen in 2024.
Aaron Rodgers and the Jets take this.
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— New York Jets (@nyjets) August 12, 2024
2024/25 NFL Week 2
See who clashes in the opening act of the NFL season with this Week 2 game schedule.
Matchup | Time | TV | Location | |
---|---|---|---|---|
Thursday, September 12, 2024 | ||||
Buffalo | @ Miami | 8:15 PM | Prime Video | Hard Rock Stadium, Miami Gardens, FL |
Sunday, September 15, 2024 | ||||
New Orleans | @ Dallas | 1:00 PM | FOX | AT&T Stadium, Arlington, TX |
Tampa Bay | @ Detroit | 1:00 PM | CBS | Ford Field, Detroit, MI |
Indianapolis | @ Green Bay | 1:00 PM | FOX | Lambeau Field, Green Bay, WI |
New York | @ Tennessee | 1:00 PM | CBS | Nissan Stadium, Nashville, TN |
San Francisco | @ Minnesota | 1:00 PM | CBS | U.S. Bank Stadium, Minneapolis, MN |
Seattle | @ New England | 1:00 PM | CBS | Gillette Stadium, Foxborough, MA |
New York | @ Washington | 1:00 PM | FOX | Northwest Stadium, Landover, MD |
Los Angeles | @ Carolina | 1:00 PM | FOX | Bank of America Stadium, Charlotte, NC |
Cleveland | @ Jacksonville | 4:05 PM | CBS | EverBank Stadium, Jacksonville, FL |
Las Vegas | @ Baltimore | 4:05 PM | CBS | M&T Bank Stadium, Baltimore, MD |
Los Angeles | @ Arizona | 4:25 PM | FOX | State Farm Stadium, Glendale, AZ |
Pittsburgh | @ Denver | 4:25 PM | FOX | Empower Field at Mile High, Denver, CO |
Cincinnati | @ Kansas City | 8:20 PM | NBC | GEHA Field at Arrowhead Stadium, Kansas City, MO |
Monday, September 16, 2024 | ||||
Atlanta | @ Philadelphia | 8:15 PM | Lincoln Financial Field, Philadelphia, PA | |
Betting Lines for NFL Games | Week 2 Games of the NFL Season |
Wrapping Up the Jets
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AJ Epenesa NFL Defensive Rookie of the Year Odds & Analysis For 2020 Season
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Some scouts projected Iowa defensive end AJ Epenesa as a first-round pick in this year’s draft, but he slipped to the 54th pick and the Buffalo Bills. Here are Epenesa’s odds at Mybookie to win 2020 NFL Defensive Rookie of the Year as well as the Bills’ over/under win total.
Odds to win Defensive Rookie of the Year:
Bills’ win total: 9 (over -145 favorite)
Playing at Edwardsville High School in Illinois, Epenesa was an All-American in both football and track. Why did he choose to play at Iowa? His father, Eppy, walked on to the Iowa football team after moving from the American Samoa. AJ became the highest-rated recruit to play for a Kirk Ferentz-led team at Iowa.
He was named to the Big Ten All-Freshman team in 2017. He finished with 15 tackles, including eight solo stops and seven assists, along with 5.5 tackles for loss, 4.5 sacks, one pass break-up and one forced fumble. Epenesa’s first career sack came against Wyoming quarterback Josh Allen, who is now Buffalo’s starter.
“Going into that game, we knew who he was, what he’s about and what he could do,” Epenesa said. “To this day, there’s no quarterback that I’ve had to sack that was tougher than Josh Allen. He was really hard to bring down.”
As a sophomore in 2018, Epenesa was one of five national finalists for Polynesian Player of the Year and was first-team All-Big Ten. He saw action in all 13 games, leading the team in tackles for loss (16.5-81) and sacks (10.5-66) while recording 37 tackles, four pass break-ups, eight QB pressures, four forced fumbles and a blocked punt.
Then last year, Epenesa was a finalist for the Ted Hendricks Award, first-team All-Big Ten, second-team All-American and the Iowa team MVP on defense. Epenesa started every game and recorded 49 tackles, including 32 solo stops and 17 assists. He led team with 14.5 tackles for loss, 11.5 sacks, and four forced fumbles and also had nine QB pressures and three pass break-ups. In a win over USC in the Holiday Bowl, he was named the game’s Defensive MVP. Epenesa had four tackles, including three solo stops and one assist. He tied the Iowa bowl record with 2.5 sacks vs. USC, along with collecting fourth forced fumble of the season.
With the 6-foot-6, 280-pound Epenesa on the defensive line last season, the Hawkeyes won 10 games and limited opponents to 308.2 yards (196 passing, 113 rushing) and 14 points per game.
Epenesa’s best edge move around the corner is his patented swiper move. There is one problem with the swiper move, however. The success of that move is intrinsically tied to whether or not an offensive lineman actually shoots his punch at Epenesa. The Bills took him with the No. 54 overall pick.
“In a perfect world, he’ll play a backup position the first season potentially to move inside on rush situations,” Bills coach Sean McDermott said.
Epenesa lacks an explosive first step on tape but buoyed his physicality and heavy hands into high-end production at the collegiate level, finishing his career as the first Hawkeye with back-to-back seasons of double-digit sacks since Matt Roth (2003-04).
“He has strong hands and brings that edge and inside pressure,” said Mel Kiper, Jr., ESPN analyst. “He can drive an offensive tackle into the quarterback. He did a great job against (Southern California offensive tackle) Austin Jackson, who went in the first round to the Miami Dolphins.”
Epenesa now joins three other Hawkeyes who are on Buffalo’s active roster: guard Ike Boettger, wide receiver Nick Easley, and strong safety Micah Hyde. Iowa has had at least one player drafted in every NFL Draft since 1978. No school has more players on the Bills than Iowa.
“I’ve coached players that have come from that culture,” McDermott said of the school. “The minute we drafted A.J., I immediately got a couple of texts from players that I’ve coached that went to Iowa that know him or know of him or know of his family. It seems like there’s a lot of parallels between their culture and our culture here.”
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