49ers 2024 Season: Key Matchups and 49ers Season Odds

As the San Francisco 49ers embark on the 2024 NFL season with high expectations following their impressive playoff run. To help you navigate the upcoming season and make informed decisions about your 49ers season odds, we’ve compiled a comprehensive breakdown of the team’s most crucial matchups.

2024 San Francisco 49ers Top Games of the Regular Season
| MyBookie NFC Championship Team Betting Analysis to Win the Title

2024 49ers Season | 55th in the National Football League | 3rd under head coach Mike McDaniel
2023: 11–6 record / 2nd AFC East

Top Niners Games of the Regular Season

The San Francisco 49ers, because of their NFC Championship in the 2023-2024 NFL Season, have a tough upcoming schedule.

Eight games on the 49ers schedule will determine whether Brock Purdy, Christian McCaffrey, Deebo Samuel and the rest head to the playoffs the NFC’s 1-seed.

Check out a list of the San Francisco 49ers’ top games of the season.

San Francisco 49ers Schedule Breakdown

NFL Week 1 vs New York Jets

Rodgers versus Purdy should be a stellar matchup.

Not only that, but Robert Salah used to coach the SF defense.

Still, this happens on San Francisco’s field.

So Salah’s D could struggle.

Give the Niners the win.

NFL Week 3 at Los Angeles Rams

The Rams are much improved and the 49ers may or may not have their entire offensive line together.

Beating Los Angeles this season won’t be easy.

It especially won’t be easy on the road.

Jared Verse and Ernest Jones IV get to Purdy early and often.

Rams pull off the home upset victory.

NFL Week 7 vs Kansas City Chiefs

Although the Chiefs will once again be the team to beat for the Lombardi, San Francisco will have revenge on their minds.

Not only that, but by NFL Week 7, holdout Trent Williams will have gelled with his fellow offensive linemen, which means the SF offense will be rolling.

San Francisco scores the victory.

NFL Week 8 vs Dallas Cowboys

SF is at home, which means the Boys will be in trouble.

San Francisco always beats Dallas.

One of the reasons is because Kyle Shanahan knows the perfect strategy to counter the Dallas’ pass rush.

Christian McCaffrey will run right at Micah Parsons while Purdy should find holes in the Dallas’ secondary.

Niners win big.

NFL Week 12 at Green Bay Packers

Green Bay has a chance because this is at Lambeau.

But the Packers’ offense line may not be up to par, which will spell trouble.

By NFL Week 12, we’ll know a lot more.

The guess is that Purdy, McCaffrey, and Deebo get it done while the Packers’ line fold against Fred Warner and the Niners’ pass rush.

The prediction is SF wins another one.

NFL Week 13 at Buffalo Bills

Beating the Bills won’t be easy.

In fact, this could be a 49ers loss.

The reason? Buffalo’s offense should be more balanced this NFL season because Keon Coleman is a different type of wide receiver than Stefon Diggs and James Cook is ready for a breakout season.

If the game were in SF, we’d go with the Niners.

But in Buffalo, Josh Allen pulls out the win.

NFL Week 15 vs Los Angeles Rams

In the rematch, the Niners get it done.

This game could be for the NFC West title.

If that’s the case, it’s difficult seeing Brock and his buds folding against Stafford and the Rams.

Give San Francisco the win, the NFC West title, and a step closer to home field advantage throughout the playoffs.

NFL Week 17 vs Detroit Lions

This is the game.

Detroit and San Francisco played a fantastic NFC Championship last season that went to the 49ers.

The tables will turn in 2024.

Detroit beats the Niners in this to secure home field throughout the playoffs.

The game will be close but the Lions prevail.

2024 NFL Season | San Francisco 49ers Odds
MyBookie betting lines for the NFL team based in the San Francisco Bay Area.

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Another Sunday closer to 🏈

🎟️: https://t.co/c0NW44RI7D pic.twitter.com/y9uYLIQRsm
— San Francisco 49ers (@49ers) August 5, 2024

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San Francisco 49ers Season Total Odds

To maximize your winnings on the 49ers and other NFL teams, arming yourself with in-depth analysis is crucial.

By understanding the key matchups and considering the latest 49ers season odds, you can make informed betting decisions.

Don’t miss out on the opportunity to capitalize on the excitement of the NFL season – sign up for an account now and start betting!

Also, check out the San Francisco 49ers Props for the next season.

2024/25 NFL Week 15

See who clashes in the opening act of the NFL season with this Week 15 game schedule.

Matchup		Time	TV	Location
Thursday, December 12, 2024
Los Angeles	@ San Francisco	8:15 PM	Prime Video	Levi's Stadium, Santa Clara, CA
Sunday, December 15, 2024
Kansas City	@ Cleveland	1:00 PM	CBS	Huntington Bank Field, Cleveland, OH
Cincinnati	@ Tennessee	1:00 PM	FOX	Nissan Stadium, Nashville, TN
Washington	@ New Orleans	1:00 PM	FOX	Caesars Superdome, New Orleans, LA
Baltimore	@ New York	1:00 PM	CBS	MetLife Stadium, East Rutherford, NJ
Dallas	@ Carolina	1:00 PM	FOX	Bank of America Stadium, Charlotte, NC
New York	@ Jacksonville	1:00 PM	FOX	EverBank Stadium, Jacksonville, FL
Miami	@ Houston	1:00 PM	CBS	NRG Stadium, Houston, TX
Indianapolis	@ Denver	4:25 PM	CBS	Empower Field at Mile High, Denver, CO
Buffalo	@ Detroit	4:25 PM	CBS	Ford Field, Detroit, MI
Pittsburgh	@ Philadelphia	4:25 PM	FOX	Lincoln Financial Field, Philadelphia, PA
New England	@ Arizona	4:25 PM	CBS	State Farm Stadium, Glendale, AZ
Tampa Bay	@ Los Angeles	4:25 PM	FOX	SoFi Stadium, Inglewood, CA
Green Bay	@ Seattle	8:20 PM	NBC Peacock	Lumen Field, Seattle, WA
Monday, December 16, 2024
Chicago	@ Minnesota	8:00 PM		U.S. Bank Stadium, Minneapolis, MN
Atlanta	@ Las Vegas	8:30 PM		Allegiant Stadium, Las Vegas, NV
Betting Lines for NFL Games \| Week 15 Games of the NFL Season

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San Francisco 49ers Top Games of the Regular Season

Previous Betting News

In about a week, NFL training camps open for the 2022-2023 regular season. With about 7 days to go before the start of training camps, few rumors abound. One, though, involving San Francisco’s starting quarterback, is huge. Check out the latest NFL Betting news on Jimmy G, the suspension the NFL is likely to hand Deshaun Watson, a rumor regarding a retired former Super Bowl winning coach, and what’s going on with Arizona’s quarterback.

NFL Rumors, Trades, Free Agents & Betting News | July 20th Edition

2022-23 NFL Regular Season

When: Sep. 8, 2022 – Jan. 8, 2023

If no trading partner shows up, the 49ers may cut Jimmy G

The 49ers are desperate to trade Jimmy GQ. The Super Bowl quarterback enters training camp after recovering from shoulder surgery, which might be the reason so many teams are chilly on the signal-caller.

If the Niners don’t make a trade, rumor has it SF will dump last season’s starter. The problem is that Garoppolo is due to make $26.5 million this season. His cap hit is tremendous and SF must extend both Nick Bosa and Deebo Samuel.

Expect the 49ers to cut Jimmy. It makes no sense for SF to pay Garoppolo that amount of money when Deebo is so unhappy and Bosa could be gone after this season.

Browns believe Watson’s suspension will be 8 games

Most NFL analysts believe the NFL will suspend Deshaun Watson 2 to 8 games. The Cleveland Browns are making plans for the high-end.

A 2-game suspension is a sort of slap in the face to his accusers. An 8-game suspension signals the NFL took the allegations of sexual misconduct seriously and listened to Deshaun’s accusers.

In Watson’s favor? No criminal charges and the Texans settling for their part in all of this. Still, Cleveland doesn’t want to take any chances.

One of the craziest rumors floating around is that the Browns will trade for 49ers’ quarterback Jimmy Garoppolo and start Jimmy G. until Watson returns.

Former Saints’ coach Sean Payton said he can’t predict when or where he will return

This rumor won’t affect the upcoming season, but, no doubt, there are fans for some NFL teams giddy with excitement. Sean Payton, one of the winningest coaches in NFL history, recently said he believes he’ll be an NFL coach again.

Payton also said he didn’t know when he’ll head back to league and he didn’t know where he’ll end up. Three teams that appear to be on Sean’s radar are the Dallas Cowboys, Los Angeles Chargers, and Carolina Panthers.

If Payton returns to coaching in 2023, it will likely be with the Panthers. The Bolts and Cowboys are Super Bowl contenders. Both teams should make the playoffs and both have a real shot at winning their respective conference.

Sean Payton is a great coach. But neither Jerry Jones, Dallas’ owner, nor Dean Spanos, who owns the Los Angeles Chargers, will want to rock the boat with a new coaching hire after a successful season.

A week before training camps open and the Cardinals have yet to commit to Kyler Murray

Rumor has it, the Arizona Cardinals are about to help Kyler Murray take the next step from super rich to uber rich.

Most believe the Desert Birds will hand Murray a super-max contract. But although the rumor is likely true, Arizona has yet to actually give Kyler a contract.

So what does that tell us? Maybe, it means nothing. Or it could mean the Cardinals want to unload their starter for pieces that help them win in the long run.

Arizona ended their season losing 6-of-10. The losses weren’t all Murray’s fault. But a few of the losses were pathetic. Zona had no business losing 30-12 to Detroit, 34-10 against Carolina, and 38-30 at home versus Seattle in week 18.

It’s apparent that the Cardinals don’t have a great defense, not when you make Jared Goff and P.J. Walker, he started for the Panthers, look like top-class signal-callers. If your Zona, do you really want to hand your undersized QB a max deal when your defense is lousy?

We’ll see what happens, but the rumor of a max contract may be a rumor.

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