MLB Week 16 Betting Picks for the Top Games On the Weekend

MLB has another great weekend of excellent baseball action. On Friday, Cleveland heads to Tampa, and Houston hosts Seattle. Then on Saturday, the Yankees take on the Royals and the Cubs battles the Giants. On Sunday, the Twins battle the Padres. Check out analysis and free straight up MLB Betting picks for six of this weekend’s top games.

Week 16 Winning SU Picks for the Weekend Action | MLB Betting Predictions

Top MLB Picks for the Weekend

When: Friday, July 29 – Sunday, July 31

Cleveland Guardians at Tampa Bay Rays

When: Friday, July 29

The Guardians send ace Shane Bieber to the mound on Friday hoping to score a victory versus the home team Rays. But although Bieber remains Cleveland’s ace, he hasn’t had the best season.

Shane’s ERA is a decent 3.55. His record, though, is 4-6. Bieber has thrown to Rays’ batters just 22 times. That’s not enough to say whether he’ll be effective.

Tampa starter Jeffrey Springs is 3-2 with a 2.50 ERA. Springs should pick up his fourth victory of the season.

MLB Pick: Tampa Bay Rays

Seattle Mariners at Houston Astros

When: Friday, July 29

Mariners versus Astros on Friday could be a great pitchers’ duel. Seattle sends Robbie Ray to the mound while Houston goes with Justin Verlander.

Ray is 8-7 with a 3.90 ERA. Verlander is 13-3 with a 1.88 ERA. The Astros’ ace is 6-1 and has a 2.05 ERA at home. Ray will pitch well, but it won’t be well enough. Stros win.

MLB Pick: Houston Astros

Kansas City Royals at New York Yankees

When: Saturday, July 30

Yankees starter Nestor Cortes is having a great season. At home, Cortes is 3-1 with a 1.90 ERA and has struck out 53. Overall, Cortes’ ERA is a terrific 2.48.

KC goes with former Cy Young winner Zack Greinke. The 38-year-old isn’t having a great season. Greinke is 0-5 on the road this year. He’s got a 7.38 road ERA.

Cortes and the Yankees should win. If you’re feeling lucky, back the Yankees on the run line.

MLB Pick: New York Yankees

Chicago Cubs at San Francisco Giants

When: Saturday, July 30

Chicago starter Drew Smyly’s away stats are more impressive than his home stats. Smyly is 3-2 with a 3.71 ERA in away games.

The Giants send Jakob Junis to the mound. Junis is 4-2 with a 2.98 ERA. In home games, Junis is 2-0. But Jakob’s ERA when throwing in San Francisco’s park is 4.03. Smyly and the Cubs have a chance.

MLB Pick: Chicago Cubs

Detroit Tigers at Toronto Blue Jays

When: Sunday, July 31

Jose Berrios and the Toronto Blue Jays have a huge advantage versus Garrett Hill and the Detroit Tigers. In away games, Hill is 0-2 with an 8.10 ERA.

Berrios doesn’t have overall great stats, but at home, he’s thrown well. Jose’s ERA in Toronto is 3.47. He’s struck out 64 batters and is 5-0. The Jays win.

MLB Pick: Toronto Blue Jays

Minnesota Twins at San Diego Padres

When: Sunday, July 31

Twins’ starter Dylan Bundy’s away ERA isn’t great at 6.41. But he’s 3-3 on the road.

The Friars counter with Sean Manaea. San Diego’s Sunday starters is 3-3 at home. The former A’s ace has a 4.53 ERA on the road. San Diego should be a huge favorite going into this. Minnesota will be worth a look for sure.

MLB Pick: Minnesota Twins

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