San Francisco 49ers Odds: Calendar’s Win/Loss Betting Analysis

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We are still coming down from the draft and going over the selections made by each team, trying to judge what sort of impact those players might make. Given where we are at in the offseason, it does seem a little odd to start talking about the regular season, which is still months away, but that’s just how excited we are about what is to come. The official NFL schedule is still to be released, but we do know who every team will play this season. It’s just a matter of putting dates and times to those matchups. With that in mind, we can somewhat break down the schedule for each team, with the focus on the San Francisco 49ers NFL betting analysis for this piece. Let’s look at their opponents, home and away, to try and figure out how they might do.

2023 Analysis of Team-By-Team Opponents without calendar: San Francisco 49ers – Home/Away

Home

The 49ers ended the season with a 13-4 record, winning 10 straight to close out the year, whilst also making it to the NFC Championship Game, which they lost to Philly. Their run was propelled by 3rd string QB Brock Purdy, who will take the reins this season. The 49ers were great at home last season, going 8-1. They swept their division opponents – Seahawks, Rams, and Cardinals – and will once again try to make their home field a fortress. Let’s look at which teams they will face this season, with their overall and road records in parentheses. They have a tough one against the Baltimore Ravens (10-7, 5-4) and another hard matchup against the Cincinnati Bengals (12-4, 6-3). The Dallas Cowboys (12-5, 4-4) and the New York Giants (9-7-1, 4-4) will also pay a visit. The 49ers will also take on the Tampa Bay Buccaneers (8-9, 3-5), who will start life without Tom Brady under center.

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Away

As you can see, the home schedule for the San Francisco 49ers is brutal, which tends to happen after a successful season. Still, given how good they were on home turf in 2022, you still expect them to win more than their fair share in their own building. As for road games, they will, of course, meet all their divisional opponent, who they also swept on the road last season. San Francisco looks to be the cream of this division but repeating at 6-0 will still not be easy. Let’s take a peek at their other road opponents, as well as their overall and home records.

Who knows what to expect from the Cleveland Browns (10-7, 4-4) this season, but the 49ers will soon find out. They will have another AFC North trip, this time to Pittsburgh to face the Steelers (9-8, 4-4). One of the biggest games on the 49ers schedule is a rematch with the Philadelphia Eagles (14-3, 7-2). Games against the Washington Commanders (8-8-1, 4-5) and the Minnesota Vikings (13-4, 8-1) are also on tap, as is a trip to the resurgent Jacksonville Jaguars (9-8, 5-3).

Not an easy schedule by any stretch of the imagination for the San Francisco 9ers, but this is a team that set a high bar with their performance in 2022. Matching their win total from last season seems unlikely, but this still looks like a double-digit win team to me, assuming that Brock Purdy does not have a huge drop off.

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San Francisco could be on the cusp of trading Jimmy Garoppolo and they’re still on the higher end of this season’s NFL win-loss totals. SF’s game total for the season is 9 ½. The total puts the 49ers in company with fellow NFC West team Arizona, the Indianapolis Colts, Tennessee Titans, and Cincinnati Bengals. Check out why the Niners will win more than 9 games, why San Francisco won’t, and an SF NFL Win Loss Total Betting prediction. 

Seahawks 2022 NFL Season Betting Prediction: Win/Loss Record

2022-23 NFL Regular Season

When: Sep. 8, 2022 – Jan. 8, 2023
San Francisco 49ers Total Win-Loss Total Odds: 9 ½  

Why the San Francisco 49ers will win more than 9 games

Whether San Francisco trades Jimmy G. or not, the 49ers are set at quarterback. Trey Lance is more than capable of leading the team.

So if Jimmy is out the door, SF will be okay. If Garoppolo stays, San Francisco should be better than okay. Kyle Shanahan can choose to start Jimmy if he feels Trey requires more seasoning, or he could start Lance.

If it’s Garoppolo, Shanahan calls drop back passes. If it’s Lance, Shanahan calls more out of the pocket on the run passes. The 49ers’ head coach might even call quarterback runs if Trey is the starter.  

No matter who ends up under center for San Francisco, the 49ers look strong. The defense, led by end Nick Bosa and free safety Jimmie Ward, remains one of the top units in the league. 

The offensive line is stacked. Running back Elijah Mitchell is going to have a great season. George Kittle is one of the top tight-ends in the NFL and wide receiver Deebo Samuel might be the overall best skill player in the league. 

Why the San Francisco 49ers won’t win more than 9 games

The schedule is tough. Not only must the 49ers play against their fellow NFC West teams, Arizona, Seattle, and the Super Bowl Champions, the LA Rams, but the NFC West plays the AFC West this season.

Every team in the AFC West is a playoff contender. Las Vegas traded for wide receiver Davante Adams, the Chargers improved their defense big time, Patrick Mahomes still throws for the Chiefs, and Denver traded for Russell Wilson.

Also on San Francisco’s schedule are matchups versus Miami, New Orleans, Washington, and Tampa Bay. None of those games are for sure victories. 

Final Betting Analysis: Will the San Francisco 49ers win at least 10 games?

Trey Lance could be a star but Lance is unproven, which makes it difficult to back the Niners to win more than 8 to 9 games. 

Yes, there’s a chance Garoppolo stays in a 49ers’ uniform. But the better chance is that he ends up playing somewhere else. And even if Jimmy stays, he’s injury-prone. So Lance will end up starting a few games for sure. 

Teams with questions at quarterback are tough to get behind to cover win-loss totals. San Francisco has two decent quarterbacks on their roster. 

But one is inexperienced and the other won’t finish the season without suffering an injury. The brutal schedule makes under the play.  

San Francisco 49ers Win Loss Total Pick: Under 9 ½  

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It is always tough to look at any team prior to training camp and start predicting how many wins they might come away with in the coming season. Things get even trickier when you don’t really know who will be starting under center on opening day. All of that brings us to the San Francisco 49ers and their current QB situation. The thought was that Jimmy Garoppolo would be gone in the offseason, but he is still in San Francisco as we speak. That said, the 49ers drafting Trey Lance suggests that Jimmy G is on borrowed time. I would be paying attention to who wins that battle before making any wild predictions for the Niners this season. For now, let’s see if we can try and make a prediction or two so you can start planning your bets against their NFL Team Totals odds.

San Francisco 49ers Win/Loss Betting Odds and Prediction for the 2021-22 Season

49ers Divisional and Playoff Chances

The 49ers went into the 2020 season with a bit of a Super Bowl hangover after gassing the championship game late and losing to the Kansas City Chiefs. That aside, they were viewed by many as a legitimate threat to make another deep run, but that quickly fell apart as the injuries began to pile up. To say that the Niners were hammered by the injury bug is perhaps putting things rather mildly, so ending the season at 6-11 was not really an unexpected outcome given how things played out. The NFC West went to the Rams, who look to be even better this season.

Divisional matches are always important, but in the West, they might be crucial in deciding who wins this division. As it stands now, the 49ers are in at +210 to win the division, just behind the Rams, who are in as the favorite.

49ers 2021 Schedule and Win Total

The bookies have the 49ers win total for the coming season set at 10 ½, a number that might change once we find out who will be named the starter. If the 49ers can stay healthy, they have a bunch of playmakers on both sides of the football, and especially in the running game, which could take some of the pressure off of whomever starts at QB.

The 49ers start the season with a pair of games on the road, but you have to say that they are both winnable, as the Lions and Eagles are not the best the league has to offer. Let’s also remember that the 49ers had a winning record on the road last season. Their next 3 games include a pair of divisional games and 2 of 3 at home. By the time we hit the end of Week 5, we could well be looking at a team that is sitting at 4-1. If they can get out to that kind of start, they have a schedule ahead of them that could potentially set them up nicely for a season where they register double-digit wins.

Call it sitting on the fence if you must, but I am a little nervous about making a prediction for a team that does not yet know its starting QB. That said, the 49ers have more than enough weapons to win a lot of football games, so 11 or 12 wins this season is not out of the question.

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While former Atlanta Falcons offensive coordinator Kyle Shanahan is one of the most respected offensive minds in all of football, the current head coach of the San Francisco 49ers is now in need of some improved results after winning just 10 games in his first two seasons with the rebuilding franchise.

After an uninspiring 6-10 mark In 2017, the Niners went a discouraging 4-12 last season and while Frisco’s progressions was probably slowed by the unexpected and ill-timed ACL tear from starting quarterback Jimmy Garoppolo, all of the team’s struggles can’t be blamed on the loss of their still-inexperienced signal-caller.

Now, with San Francisco hoping for a successful return from ‘Jimmy G’ the NFC West playoff hopefuls are desperate to start winning. Will Frisco finally take a step forward or will the upcoming 2019 campaign result in the franchise’s fifth consecutive losing season?

Will Shanahan survive if the 49ers don’t start playing better or is this the beginning of the end of an era that never quite got off the ground?

Thanks to the expert NFL predictions that you’re about to get on each and every game on San Francisco’s upcoming 2019 docket, you’re going to have a great idea of just how many games the 49ers will win this coming season.

San Francisco finished the 2018 season ranked 21st in scoring (21.4 ppg) and a discouraging 28th in points allowed (27.2 ppg). To address their offseason needs, the Niners drafted Ohio State defensive end Nick Bosa with the second overall pick before adding South Carolina wide receiver Deebo Samuel and Baylor wideout Jalen Hurd in the second and third rounds respectively.

The 49ers also added former Buccaneers linebacker Kwon Alexander, former Falcons running back Tevin Coleman and former Eagles wide receiver Jordan Matthews in free agency among others.

San Francisco 49ers 2019 NFL Season Win/Loss Total Odds & Betting Predictions

Week 1 at Tampa Bay

The Buccaneers will almost certainly be better in 2019 than they were a year ago because of the hiring of no-nonsense head coach Bruce Arians. With that said, I like Tampa Bay to take care of business in their regular season and home opener. Loss. 0-1.

Week 2 at Cincinnati

I’m not expecting a whole lot out of Cincinnati in 2019, but I like the Bengals to hold it down at home in a game it looks like they should win. Loss. 0-2.

Week 3 vs Pittsburgh

Things won’t get any better now that the 48ers are back at home. Pittsburgh is basically the superior team on both sides of the ball. Loss. 0-3.

Week 4 BYE

Week 5 vs Cleveland

This week 5 matchup should be a fun-filled thriller between two teams with young and talented quarterbacks that are looking to improve. I like Frisco to take care of business out of sheer desperation and the fact that they’re playing at home. Win. 1-3.

Week 6 at LA Rams

Frisco suffered a 48-32 road loss against the Rams to cap off their 2018 season a year ago and I don’t see them coming close to getting the road upset in this Week 6 meeting either. Loss. 1-4.

Week 7 at Washington

The Skins were pretty decent in winning seven games a year ago despite losing starting quarterback Alex Smith to a season-ending injury. Washington has question marks at quarterback, but the Skins manage to take care of business in this one. Loss. 1-5.

Week 8 vs Carolina

I’m expecting Cam Newton and Carolina to bounce back in a big way in 2019 after their subpar 7-9 mark a year ago. The Panthers are the far better defensive team and this just looks like a matchup they should win despite being on the road against the Niners. Loss. 1-6.

Week 9 at Arizona

While everyone associated with the Niners will be ready to press the panic button by the time this matchup rolls around, I’m going to say that Arizona manages to hold it down at home in a shootout after sweeping Frisco a year ago. Loss. 1-7.

Week 10 vs Seattle

This looks like a game that Seattle should win, but they won’t. San Francisco will be completely and utterly desperate and they always seem to play the division rival Seahawks tough at least once per year. After getting the 26-23 overtime upset win at home in Week 15 last season, San Francisco manages to make it two straight at home over Russell Wilson and company. Win. 2-7.

Week 11 vs Arizona

Sheer desperation, combined with the fact that they’re playing at home will be the two driving forces that put San Francisco over the top in this Week 11 divisional date. I’m expecting to see a more cohesive Frisco team by this juncture of the season as well. Win. 3-7.

Week 12 vs Green Bay

The Niners fell to the Packers 33-30 at Lambeau Field in Week 6 last season and I’m going to say they repeat their feat despite being on the road this time around. Simply put, I’m expecting Aaron Rodgers to put on a show in this one against a Niners defense that just doesn’t look very scary on paper. Loss. 3-8.

Week 13 at Baltimore

Baltimore’s lockdown defense puts the clamps on Jimmy G and Lamar Jackson mostly avoids meeting Nick Bosa face-to-face. Loss. 3-9.

Week 14 at New Orleans

There’s no way the 49ers go down to the Big Easy and beat a focused Drew Brees and the high-scoring Saints with New Orleans’ almost assuredly locked in on their impending playoff positioning. Loss. 3-10.

Week 15 vs Atlanta

The Niners will be going all out to get this much-needed win but it’s not going to happen for the same reason they lose to New Orleans in Week 14. Atlanta will be focused on reaching the playoffs and they’ve got the edge at quarterback. Loss. 3-11.

Week 16 LA Rams

The Niners were blown out of the water in their 39-10 Week 7 home loss against the Rams a year ago and they’re going down in similar fashion in this Week 16 meeting as well. Loss. 3-12.

Week 17 at Seattle

The Niners got smacked senseless in their 43-16 Week 13 road loss against the Seahawks a year ago and with Seattle focused on reaching the playoffs in this contest, I’ve got Frisco going down again, like, really hard. Loss. 3-13.

With so much uncertainty, I just don’t see San Francisco having a very successful 2019 season. With that said, I clearly don’t see five wins for the 49ers in 2019. Bet the Under NFL betting enthusiasts.

Previous Betting News

San Francisco 49ers fans and football prognosticators are expecting the Niners to take a significant leap forward because of the late-season play of new franchise quarterback Jimmy Garoppolo a year ago. You see, after being acquire in a trade with the New England Patriots last season, Jimmy G as he’s called by many, won each of the five games he started to close out Frisco’s 2017 campaign on a seriously high note. Now, football fans and betting enthusiasts everywhere believe San Francisco is poised to improve in a big way in 2018.

If you’re looking to cash in on San Francisco’s regular season win total odds and you need a bit of assistance with figuring out just how many games the 49ers will win this coming season, then look no further. I’ve got you covered NFL betting enthusiasts!

San Francisco 49ers 2018 NFL Win/Loss Odds Prediction

• San Francisco 49ers Regular Season Win Total Odds – 8.5

Week 1: Sunday, Sept. 9, at Minnesota Vikings, 1 p.m. ET

The Niners are definitely going to be better in Year 2 of the Mike Shanahan era, but this is a team that also ranked 25th in points allowed last season and just 21st in rushing. The Vikings are loaded and have some legitimate Super Bowl hopes. Loss. 0-1.

Week 2: Sunday, Sept. 16, vs. Detroit Lions, 4:05 p.m. ET

Jimmy G outduels Detroit’s Matthew Stafford in a matchup featuring two of the league’s highest-paid quarterbacks. Plus, I don’t like Detroit’s hiring of Matt Patricia very much right now. Win. 1-1.

Week 3: Sunday, Sept. 23, at Kansas City Chiefs, 1 p.m. ET

Second-year signal-caller Patrick Mahomes outguns Garoppolo at home to lead the Chiefs to a win in always difficult Arrowhead Stadium. Loss. 1-2.

Week 4: Sunday, Sept. 30, at Los Angeles Chargers, 4:25 p.m. ET

The Chargers look like the better team in this affair. The Bolts have a pair of monster pass rushers and a veteran quarterback that is far more accomplished than Garoppolo. Loss. 1-3.

Week 5: Sunday, Oct. 7, vs. Arizona Cardinals, 4:25 p.m. ET

The Cardinals have been the far better team in this NFC West division rivalry in recent season, but no more. The Niners win at home against the Cards who are playing for a first-year head coach in Steve Wilks. Win. 2-3.

Week 6: Monday, Oct. 15, at Green Bay Packers, 8:15 p.m. ET

Aaron Rodgers shows Jimmy G a thing or two about playing quarterback in the NFL in what looks like one of the more intriguing Monday Night Football matchups on this year’s schedule. Loss. 2-4.

Week 7: Sunday, Oct. 21, vs. Los Angeles Rams, 8:20 p.m. ET

This Sunday night matchup looks like a thriller just waiting to happen In the end though, the Rams are the better team on both sides of the ball and have some legitimate Super Bowl hopes from where I’m sitting. Loss. 2-5.

Week 8: Sunday, Oct. 28, at Arizona Cardinals, 4:25 p.m. ET

The Cardinals are starting Sam Bradford this season…well…unless he’s injured, which could certainly be the case. Either way, I like the Niners to get the regular season sweep. Win. 2-6.

Week 9: Thursday, Nov. 1, vs. Oakland Raiders, 8:20 p.m. ET

The longtime Bay Area rivals will meet in prime time for the final time before the Raiders bolt for Los Angeles. I’m expecting this one to be an absolute thriller that the Niners narrowly bag in a high-scoring shootout. Win. 3-6.

Week 10: Monday, Nov. 12, vs. New York Giants, 8:15 p.m. ET

The Niners get back-to-back wins in this one because the Giants are rebuilding and will be dealing with the effects of jet-lag. Win. 4-6.

Week 11: BYE

Week 12: Sunday, Nov. 25, at Tampa Bay Buccaneers, 1 p.m. ET

The Buccaneers are going to be completely and utterly desperate for a victory by the time this Week 12 contest rolls around, but I don’t like Dirk Koetter and I don’t believe the Bucs have much direction at all. Frisco gets the road win in this one. Win. 5-6.

Week 13: Sunday, Dec. 2, at Seattle Seahawks, 8:20 p.m. ET

Richard Sherman would like nothing better than to beat his old team, but it’s not happening. Seattle is still difficult to beat at home and they’ll be completely locked in for this Week 13 showdown. Loss. 5-7.

Week 14: Sunday, Dec. 9, vs. Denver Broncos, 4:05 p.m. ET

The Niners narrowly get past a Broncos team that will be better offensively in 2018 than they’ve been the last couple of seasons, but just doesn’t look nearly as powerful defensively as in years past. Win. 6-7.

Week 15: Sunday, Dec. 16, vs. Seattle Seahawks, 4:05 p.m. ET

These NFC West rivals will square off for the second time in three weeks, but I’m expecting an identical result to their prior meeting as Russell Wilson will be the best player on the field and Seattle’s defense narrowly outplays Frisco’s. Loss. 6-8.

Week 16: Sunday, Dec. 23, vs. Chicago Bears, 4:05 p.m. ET

The Niners get the big home win over a Bears team that is rebuilding under first-year head coach Matt Nagy. This one will be intriguing – and close – but the Niners are the pick to hold it down at home. Win. 7-8.

Week 17: Sunday, Dec. 30, at Los Angeles Rams, 4:25 p.m. ET

Again, the Rams are the better team on offense and by far, the better team on defense. Los Angeles will be looking to hit the postseason with some momentum and they’ll get the solid road win in this regular season finale. Loss. 7-9.

Could the NFC West be on the line in this game? It’s possible. If it is, this should be the best atmosphere yet for a Rams game since their return to the City of Angels. The Niners are improved, but the Rams are positioned to make a deep postseason run. In this burgeoning rivalry, it only seems right the Rams and Niners split the season series. Record: 10-6

Previous Betting News

Training camp is a time for optimism for every team in the NFL, but if we are being honest, the San Francisco 49ers look like the least-talented team in the NFC. They are more likely to get the first overall pick in the 2017 NFL Draft than make the playoffs this year. San Francisco has a wins total of 5.5 on NFL lines.

Analysis on the 2016 San Francisco 49ers Season Win Total Prediction

Total Win/Loss Odds Overview

After Jim Harbaugh’s departure to Michigan following 8-8 season and first missed playoffs in four years in late 2014, 49ers were even worse last season under first-year coach Jim Tomsula. Promoted from defensive line coaching spot, he was one-and- done before Chip Kelly was hired.

The rebuilt 49ers figure they have more depth than last season and having the league’s toughest strength of schedule will put that theory to the test, and early. A short week to start the season — opening at home on Monday Night Football against the Rams, followed by trips to Carolina and Seattle — could be an early-season killer, just like last year.

Kelly will take what he learned in Philadelphia and likely be a better coach with the Niners. But in a very tough division, that may not show up for a couple years, until he can get good play out of the quarterback position and be competitive on defense in a very good defensive division.

Why Bet On The Over?

The 49ers did get some good news this week. After a one-year hiatus, offensive lineman Anthony Davis is aiming to return to the NFL. The onus now falls on the NFL to allow Davis’ reinstatement and the 49ers to clear a spot on their 90-man roster should they want to retain his rights. Davis is currently on the reserve/retired list. Davis, 26, started 71 games in five seasons for the 49ers before he walked away. While San Francisco has needed help at right tackle since Davis’ departure, it’s unclear whether the team plans to keep him upon reinstatement.

The 49ers’ run-first offense was derailed early in the 2015 season when Carlos Hyde suffered a stress fracture in his foot in a Week 5 loss to the New York Giants. Hyde wound up playing on the injury in the next two games, but the pain was too much and it limited his production. After the injury, he averaged just over three yards per carry on 31 attempts before giving the foot time to heal. Hyde didn’t go on injured reserve until Dec. 11, almost six weeks after his last game against the Seahawks. If Hyde can stay healthy, he has the skill set to thrive Kelly, who runs a similar offense to what Hyde played in at Ohio State under Urban Meyer.

Why Bet On The Under?

The big question during the offseason was whether QB Colin Kaepernick would be traded. He wasn’t, and after multiple surgeries, the Niners’ former starter said he is ready to get his job back. The only problem is that Blaine Gabbert is standing in his way. At his zenith, which was a mere two offseasons ago, Kaepernick was dubbed as one of the greatest quarterbacks in league history. After three surgeries — left shoulder, right thumb, left knee — and a trade request that fell on deaf ears, this is likely a make-or-break season for him.

Gabbert has a good grasp of Kelly’s offense, and many in the organization see him as a better fit than Kaepernick, whose passing acumen has been questionable at times. Kaepernick is clearly the better athlete and has a new attitude following his tumultuous 2015.

Last season, the 49ers defense allowed 2,020 rushing yards (fourth most in the NFL) and 20 rushing touchdowns (tied for the most in the league). This season, the Niners’ run defense could be even worse. Their best run-stuffing defensive lineman, Ian Williams, who started 16 games at nose tackle last season, is injured and probably won’t participate in training camp or the preseason. He’s not sure thing for Week 1, either.

My Betting Prediction

The 49ers might not be favored in a single game. Definitely go under on NFL lines here.