Explore the NFL top betting Week 11 odds at MyBookie for insights, strategies and updates to enhance your game day experience.
NFL Football Lines Week Eleven
Top NFL Week 11 Matchups to Watch
2025 NFL Season | 106th season of the National Football League
Week 11: Thursday, November 13th – Monday, November 17th, 2025
BYE WEEK: Colts, Saints
Key Games to Watch and Bet
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NFL Football Lines Week Eleven
Betting 2025 NFL Week 11 Calendar Odds | Spread, Moneyline and Totals for the Matchups
Odds Subject to Change
Nov 13 – Totals 43
Jets Spread +13, Winner +610
Patriots Spread -13, Winner -1000
Nov 16 – Totals O/U 47.5
Commanders Spread +3, Winner +132
Dolphins Spread -3, Winner -170
Nov 16 – Totals O/U 43.5
Packers Spread -7, Winner -360
Giants Spread +7, Winner +260
Nov 16 – Totals 48.5
Bears Spread +3, Winner +136
Vikings Spread -3, Winner -175
Nov 16 – Totals 44
Chargers Spread -3, Winner -170
Jaguars Spread +3, Winner +131
Nov 16 – Totals O/U 42.5
Panthers Spread +3.5, Winner +157
Falcons Spread -3.5, Winner -204
Nov 16 – Totals O/U 49
Bengals Spread +5.5, Winner +185
Steelers Spread -5.5, Winner -246
Nov 16 – Totals 48.5
Buccaneers Spread +5.5, Winner +186
Bills Spread -5.5, Winner -246
Nov 16 – Totals O/U 38.5
Texans Spread -7, Winner -380
Titans Spread +7, Winner +270
Nov 16 – Totals O/U 48.5
Seahawks Spread +3, Winner TBA
Rams Spread -3, Winner TBA
Nov 16 – Totals O/U 48.5
49ers Spread -2.5, Winner -142
Cardinals Spread +2.5, Winner +111
Nov 16 – Totals O/U 44
Chiefs Spread -4, Winner -212
Broncos Spread +4, Winner +163
Nov 16 – Totals O/U 39.5
Ravens Spread -8, Winner -450
Browns Spread +8, Winner +310
Nov 16 – Totals O/U 46.5
Lions Spread +2.5, Winner +124
Eagles Spread -2.5, Winner -161
Nov 17 – Totals O/U 50
Cowboys Spread -3.5, Winner -189
Raiders Spread +3.5, Winner +146
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About the Author
- D.S. Williamson
- Since 2008, D.S. Williamson has written about sports and sports handicapping. His philosophy is value-based, meaning stats and other handicapping factors are only worth something in comparison to wagering odds. He believes money management and making value-based wagers is the single more important factor that distinguishes successful sports bettors from non-successful sports bettors.
