Explore the NFL top betting Week 17 odds at MyBookie for insights, strategies and updates to enhance your game day experience.
NFL Football Lines Week Seventeen
Top NFL Week 17 Matchups to Watch
2025 NFL Season | 106th season of the National Football League
Week 17: Thursday, December 25th – Monday, December 29th, 2025
BYE WEEK: No teams on bye.
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NFL Football Lines Week Seventeen
Betting 2025 NFL Week 17 Calendar Odds | Spread, Moneyline and Totals for the Matchups
Odds Subject to Change
Dec 25 – Totals 51
Cowboys Spread -7, Winner -381
Commanders Spread +7, Winner +286
Dec 25 – Totals O/U 43.5
Lions Spread -7.5, Winner -380
Vikings Spread +7.5, Winner +285
Dec 25 – Totals O/U 36.5
Broncos Spread -13.5, Winner -1299
Chiefs Spread +13.5, Winner +710
Dec 27 – Totals O/U 39.5
Texans Spread +1, Winner -105
Chargers Spread -1, Winner -121
Dec 27 – Totals O/U 40.5
Ravens Spread +3, Winner +130
Packers Spread -3, Winner -167
Dec 28 – Totals 48
Jaguars Spread -6.5, Winner -295
Colts Spread +6.5, Winner +220
Dec 28 – Totals 33.5
Steelers Spread -3, Winner -181
Browns Spread +3, Winner +141
Dec 28 – Totals 46
Buccaneers Spread -5.5, Winner -255
Dolphins Spread +5.5, Winner +193
Dec 28 – Totals O/U 42.5
Seahawks Spread -7, Winner -351
Panthers Spread +7, Winner +256
Dec 28 – Totals O/U 39.5
Saints Spread -2.5, Winner -155
Titans Spread +2.5, Winner +122
Dec 28 – Totals O/U 53
Cardinals Spread +7, Winner +259
Bengals Spread -7, Winner -360
Dec 28 – Totals O/U 43
Patriots Spread -13.5, Winner -1099
Jets Spread +13.5, Winner +600
TBA – Totals O/U 41.5
Giants Spread +1.5, Winner +100
Raiders Spread -1.5, Winner -128
Dec 28 – Totals O/U 43.5
Eagles Spread +1, Winner -105
Bills Spread -1, Winner -121
Dec 28 – Totals O/U 52.5
Bears Spread +3.5, Winner +139
49ers Spread -3.5, Winner -179
Dec 29 – Totals O/U 50
Rams Spread -8, Winner -420
Falcons Spread +8, Winner +295
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About the Author
- D.S. Williamson
- Since 2008, D.S. Williamson has written about sports and sports handicapping. His philosophy is value-based, meaning stats and other handicapping factors are only worth something in comparison to wagering odds. He believes money management and making value-based wagers is the single more important factor that distinguishes successful sports bettors from non-successful sports bettors.
