Featured Odds
Live Lines
United States
International
Germany
Spain
eBasketball
Russia
Austria
Czech Republic
Finland
France
Germany
Slovakia
Switzerland
Top Leagues
International Cups
England
Spain
France
Italy
Netherlands
Belgium
Iraq
Northern Ireland
Scotland
Turkey
Italy
PGA
European Tour
France
Czech Republic
LIVE eBasketball
LIVE CS:GO
LIVE Dota 2
Betting Lines
- LIVE Spain La Liga
- LIVE Bundesliga
- LIVE Italy Serie A
- LIVE Ligue 1
- MLS
- LIVE Belgium First Division A
- CAF Champions League
- LIVE FA Cup
- France Ligue 2
- France National
- Iraq Premier League
- Int. Club Friendly Games
- Italy Serie C
- LIVE Netherlands Eredivisie
- Netherlands Erste Divisie
- Northern Ireland Premiership
- Scotland Championship
- Spain Second Division
- Turkey TFF First League
- Live MMA
Live Basketball
Live Golf
Live Soccer
Live Hockey
Live Futsal
Live Table Tennis
LIVE Rugby
Live eBasketball
UFC Odds
TGL
DP World Tour
LPGA
Korn Ferry Tour
Ryder Cup
Presidents Cup - 2026
- US Open Men's Singles Odds to Win
- US Open Women's Singles Odds to Win
- Australian Open Men's Singles Odds to Win
- Australian Open Women's Singles Odds to Win
- French Open Men's Singles Odds to Win
- French Open Women's Singles Odds to Win
- Wimbledon Men's Singles Odds to Win
- Wimbledon Women's Singles Odds to Win
Grand Slam Futures
ATP Challenger Tour
- Ballon d'Or
- UEFA Champions League
- English Premier League
- UEFA Europa League
- La Liga Odds
- Serie A Odds
- Ligue 1
- English Premier League
- English Premier League To Win
- FA Cup Lines
- FA Cup Player Props
- FA Cup To Win
- EFL Cup To Win
- EFL Championship Lines
- EFL Championship Odds to Win
- EFL League One Lines
- EFL League One To Win
- EFL League Two Lines
- EFL League Two To Win
- EFL Trophy To Win
- National League Lines
- National League To Win
UEFA
Friendlies
Algeria
Argentina
Austria
Australia
Bahrain
Belgium
Botswana
Brazil
Bulgaria
Cameroon
Costa Rica
Cyprus
Czech Republic
Egypt
England
eSoccer
France
Germany
Gibraltar
Greece
Hong Kong
Hungary
India
Indonesia
Ireland
Israel
Kenya
Malaysia
Morocco
Netherlands
Northern Ireland
Poland
Qatar
Romania
Russia
San Marino
Scotland
Senegal
South Africa
Sweden
Switzerland
Thailand
Trinidad and Tobago
UAE
Vietnam
Zambia
Dominican Republic
Venezuela
Russia
Sweden
International Basketball Futures
Argentina
Australia
Brazil
China
eBasketball
France
Germany
Italy
Spain
Uruguay
eSoccer
Call of Duty
eBasketball
Counter Strike
League of Legends
Czech Republic
Norway
Sweden
Switzerland
Russia
Indonesia
Italy
Spain
International
Denmark
Russia
Sweden
Belarus
Canada
Czech Republic
Denmark
Finland
Germany
Norway
Poland
Russia
Slovakia
Switzerland
USA
International
Belgium
Brazil
France
Finland
Poland
2025 MLS Lines - Major League Soccer Betting Odds
2025 MLS Lines – Major League Soccer Betting Odds
There are currently no lines available for this sport. Either there are no odds open to bet on, or the sport is not in season at this time. You can check back soon or bet on any of the online sportsbook lines and betting odds listed below:
The 2024 MLS Cup Final Pick is set to be a thrilling showdown between the LA Galaxy and the New York Red Bulls, as both teams fight for the ultimate prize in Major League Soccer. With a historic championship legacy on the line for the Galaxy and the Red Bulls looking to make a Cinderella run as the lowest seed, this final promises to deliver high drama.
Read MoreMLS Lines | US Football Betting
Major League Soccer Odds | Bet the men’s professional soccer league, which represents the sport’s highest level in the United States.
MLS betting lines with MyBookie.
Create Your MyBookie Account
Sign up for an account with MyBookie MLS today and explore our diverse betting lines and props for MLS Soccer.
MLS Odds
The best Soccer tournament in the United States is here to bet on at MyBookie, whether in the Regular Season or the Postseason, you will find teams with great relevance and that have marked the statistics in recent years, teams like York Red Bulls, Seattle Sounders or Inter Miami.
We are one of the betting sites where you can review future bets, as it allows you to plan ahead every week that there are games to bet on MLS.
MLS Spreads
We offer the latest live MLS lines, team totals, spreads and money lines on Major League Soccer, which we will briefly discuss below. The daily soccer Spreads you can view are updated daily based on various competitive parameters used by our industry experts.
The MLS betting odds we offer on our players are the latest you can find in the market, with the moneyline adjusted to the team most likely to win the match, taking into account injuries and other key factors.
And in regard to the totals, it’s a real challenge that we are happy to take on to keep them up to date, so you can make the best profit by placing your bets wisely with MyBookie.
MLS Cup Odds
In addition to the Regular Tournament, MLS is a complete sport, as it has its own Cup tournament in which you can bet and win with 100 different opportunities with teams representing professional, amateur and Major League Soccer affiliated clubs.
Betting the Leagues Cup
Also bet on the international tournament organized by the MLS and Liga MX. That’s how it is! Since we have all the betting lines for all the matches between the rivalries of teams from the United States and Mexico, competing at the highest level until reaching the Final.
MLS Betting Odds
Are you one of those who bet on the winners? It is a fact that you can win with the first places, and if it is with Messi’s team, you will have more chances to win a few dollars for the weekend. So taking into account Inter and the first 3 places of each Conference seems to be a wise bet.
Or maybe you are one of those who prefer to bet on underdogs, as betting against them is synonymous with profit as well, often depending on injuries, manager changes or some circumstance that affects the team’s performance.
For example, let’s look at the cases of Chicago Fire and SJ Earthquakes:
Both in last place with no clear chance of going to the playoffs or final series, then, that’s when you decide to plan a bet against, as their negative streak is likely to continue, and you’ll get your strategies right.
MLS Futures | Champion Odds
Don’t miss the MLS Scores every week to know what happens with your favorite teams.
What team are favored to win the MLS 2025? Stay close with MyBookie to start planning the next Season, with Inter Miami +300, Galaxy +550 and LAFC +750 as the top favored teams. The Major League Soccer will begin on February 22, with San Diego FC’s first match.
US Football Betting | USA Soccer Lines, Props & Specials @ MyBookie
Experience the thrill of US football betting with our competitive odds on US’s top leagues.
Sign up for MLB betting lines and bet on your favorite teams. Don’t miss a beat – get started today and follow every goal
MLS Betting Analysis
We provide you with news information and expert analysis, which come together to complement the best information available that you can use in your MLS picks in a more accurate way, complement your betting plans and see on the horizon the teams that They can win the MLS, the Cup and the Leagues Cup.
Love betting Soccer? We have for you the 2025 MLS Soccer Betting Odds, lines and Soccer News for all Year’s Games.
2024 MLS Cup Final Pick Plus Prediction for the Game to Win it All
2024 MLS Cup Conference Final Preview and Predictions for Each Game
2024 MLS Cup Betting Lines for the Conference Semifinals Plus Winning Picks
MLS Cup: Round One Match 3 Games Betting Preview
United States Betting : Your Home for American Lines on All Major Leagues with MyBookie
US College Sports |
---|
College Football |
College Basketball |
US Soccer |
---|
MLS |
USL Championship |
USL League One |
Major US Events |
---|
PGA U.S. Open |
US Open Tennis Championships |
US Darts Masters |
More US Sports |
---|
AHL |
3HL |
MILB | Little League |
More US Sports |
---|
Major League Rugby |
The Basketball Tournament |
Cricket Premier League |
More US Sports |
---|
Major League Kabaddi |
USA Open Squash |
Premier Lacrosse League |