MLB Predictions: Complete Guide to Understand the Regular Season with MyBookie

MLB Predictions: Complete Guide to Understand the Regular Season with MyBookie

There are 3 important facts that you must know to make the MLB Predictions for the Regular Season 2025.

The Standings, Power Rankings of Pitchers and Hitters are the main keys to plan your bets in a effective way. Discover the shining teams and players that could transform your luck into earnings before the postseason begins.

If you think that the most valuable phase is postseason maybe you can reconsider it, because in Regular Seson you can win along the 162 games of the schedule.

With MyBookie stay up to date with Props, Game Props, Regular Season Wins and Series.

 

MLB Pitcher and Hitter Rankings

Check out the Top 5 outstanding pitchers and hitters heading into season 2025. They are pushing formard to win the Cy Young and Edgar Martinez Outstanding Designated Hitter Award, and maybe the MVP.

Last updated: Apr 22nd.

Pitchers
  • 1. Tarik Skubal, Tigers Odds AL MVP Regular Season +11000
  • 2. Paul Skenes, Pirates Odds NL MVP Regular Season +11000
  • 3. Zack Wheeler, Phillies Odds AL MVP Regular Season +17000
  • 4. Chris Sale, Braves Odds NL MVP Regular Season +20000
  • 5. Garrett Crochet, Red Sox
Hitters
  • 1. Aaron Judge, Yankees Odds AL MVP Regular Season -400
  • 2. Shohei Ohtani, Dodgers Odds NL MVP Regular Season +194
  • 2. Bobby Witt Jr., Royals Odds AL MVP Regular Season +530
  • 3. Juan Soto, Mets Odds NL MVP Regular Season +1575
  • 5. Yordan Alvarez, Astros Odds AL MVP Regular Season +5000
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Standings to include in your MLB Predictions

The positions of the teams in the standings is like an x-ray of each team’s performance during the regular season.

In general, many fans view it daily to make future plans for their bets in the American League, National League and World Series.

Favorites to win the World Series this 2025: Dodgers +228, Yankees +780, Phillies +1000, Mets +100, Braves +1350.

Here are the standings of the MLB Teams for 2025 Season.

Last updated: Apr 21st


 
American League East
Team W L % GB STRK HOME AWAY
Yankees 14 8 .636 W1 8-4 6-4
Blue Jays 12 10 .545 2.0 L2 8-5 4-5
Red Sox 12 11 .522 2.5 L1 6-4 6-7
Orioles 9 12 .429 4.5 L1 5-6 4-6
Rays 9 13 .409 5.0 L1 9-10 0-3
MLB AL East Winner Prediction: Yankees -108 to win.
 
American Central League
Team W L % GB STRK HOME AWAY
Tigers 13 9 .591 L1 8-2 5-7
Guardians 12 9 .571 0.5 W3 5-1 7-8
Royals 9 14 .391 4.5 W1 6-4 3-10
Twins 7 15 .318 6.0 L3 4-5 3-10
White Sox 5 16 .238 7.5 W1 4-8 1-8
MLB AL Central Winner Prediction: Tigers -120 to win.
 
American League West
Team W L % GB STRK HOME AWAY
Rangers 13 9 .591 L1 10-3 3-6
Mariners 12 10 .545 1.0 W2 8-5 4-5
Angels 11 10 .524 1.5 W1 4-2 7-8
Astros 10 11 .476 2.5 L1 6-6 4-5
Athletics 10 12 .455 3.0 L1 2-7 8-5
MLB AL West Winner Prediction: Rangers +111 to win.
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National League East
Team W L % GB STRK HOME AWAY
Mets 15 7 .682 W4 9-1 6-6
Phillies 13 9 .591 2.0 L1 9-4 4-5
Marlins 9 12 .429 5.5 W1 6-7 3-5
Nationals 9 13 .409 6.0 L1 5-4 4-9
Braves 8 13 .381 6.5 W3 6-2 2-11
MLB NL East Winner Prediction: Phillies +125 to win.
 
National Central League
Team W L % GB STRK HOME AWAY
Cubs 14 10 .583 L1 6-5 8-5
Brewers 12 10 .545 2.0 W1 9-4 3-6
Reds 11 11 .500 2.0 W1 6-6 5-5
Cardinals 9 13 .409 4.0 L4 8-4 1-9
Pirates 8 15 .348 5.5 L3 6-7 2-8
MLB NL Central Winner Prediction: Cubs -162 to win.
 
National League West
Team W L % GB STRK HOME AWAY
Padres 16 6 .727 W1 12-1 4-5
Dodgers 16 7 .696 0.5 W1 10-2 6-5
Giants 14 8 .636 2.0 L1 4-2 10-6
D-Backs 13 9 .591 3.0 W1 6-4 7-5
Rockies 4 17 .190 11.5 W1 3-6 1-11
MLB NL West Winner Prediction: Dodgers -649 to win.

American League Winner: Yankees +320 / National League Winner: Dodgers +135 | W: Win | L: Losses | %: Winning Percentage | GB: Games Behind | STRK: Current Streak | HOME: Record at Home | AWAY: Record when Away | X: Clinched Playoff Berth | Y: Clinched Division | W: Clinched Wild Card

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Trendings, News and MLB Predictions

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  If you are new to MLB betting, there are a few things you need to understand about betting on the sport—and one of those things is that betting on the totals is probably the most profitable way to bet on baseball, especially when analyzing the umpires and how their strike zones impact the game. If you are wondering why, … click title for full article.
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MLB Power Rankings

Let’s see what team is the No. 1 starting season 2025 at Week 3 to keep up to date your MLB predictions.

Last updated: Apr 21st

#1 Dodgers
#2 Padres
#3 Mets 1 ↑
#4 Cubs 1 ↑
#5 Phillies 2 ↓
#6 Yankees 1 ↑
#7 Giants 1 ↓
#8 Tigers
#9 Diamondbacks 1 ↑
#10 Rangers 1 ↓
#11 Red Sox 1 ↑
#12 Blue Jays 3 ↑
#13 Guardians 1 ↑
#14 Mariners 4 ↑
#15 Brewers 4 ↑
#16 Astros 1 ↑
#17 Orioles 4 ↓
#18 Reds 2 ↑
#19 Braves 3 ↑
#20 Athletics 5 ↑
#21 Angels 5 ↓
#22 Rays
#23 Royals 4 ↓
#24 Cardinals 1 ↓
#25 Nationals 1 ↓
#26 Twins 1 ↑
#27 Pirates 1 ↓
#28 Marlins 2 ↑
#29 White Sox
#30 Rockies
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What are the rule changes for MLB in 2025?

Following the previous years, 2023 and 2024 season, teams play as follows in the Regular Season, adding a couple of changes that you must consider in the MLB predictions.

  1. Thirteen matches against each of the other four teams in its own division (52 matches in total).
  2. Six or seven games against each of the other ten teams in their own league (64 games in total).
  3. Four matches against a “geographic rival” from the other league.
  4. Three games against each of the other fourteen teams in the other league, for a total of 46 interleague games.

Additionally, let’s see how the playoffs work, because they’re the second most important part of the competition, that had its last modification in 2022, expanding the group of teams in the Wild Card Round.

Moreover, the event is held in bracket format, with 12 teams, six from each league and including the three league division winners and three Wild Card teams per league.

 

How it Works

  • 1st seed: Best league record
  • 2nd seed: Winner of the second best division
  • 3rd seed: Winner of the third best division
  • 4th seed: Best record among Wild Card teams
  • 5th seed: Second best record among Wild Card teams
  • 6th seed: Third best record among Wild Card teams

For this reason, the first and second place teams will advance directly to the Divisional Series. For the Wild Card Series, the #3 seed will face the #6 seed, and the #4 seed will face the #5 seed.

 

Wild Card Series

First, the winners of each Wild Card Series advance to the Divisional Series and the losers are eliminated from the postseason.

Second, each game is played at the home stadium of the higher ranked team, in this case #3 and #4 serve as hosts.

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MLB’s rule changes to Consider this Season

What should you know about the organization’s regulations? As we have already seen, Major League Baseball has been evolving in different aspects, the rules of the game being one of them.

Runner’s Lane Widening

The runner’s lane has been widened to include the land between the foul line and the turf of the infield. The lane is marked with chalk to prevent runners from straying into foul territory.

Pitch Timer Reduction

The pitch timer has been reduced from 20 seconds to 18 seconds with runners on base. It will remain 15 seconds with the bases empty, and pitchers retain the ability to step off the plate and reset the clock twice per plate appearance without penalty.

Base Blocking Guideline

This is a guideline to the existing rule, and grants the runner the base when it is determined that the fielder has impeded the runner’s progress while not in possession of the ball and was not in the act of fielding the ball.

Pace Adjustments

There are a few other changes intended to tighten things up:

  • 1. Pitching Changes: The clock will be reset to 2 minutes, instead of 2:15 if a new pitcher enters the warning zone with less than 2 minutes left on the inning break clock.
  • Mound visits: Reduced from five to four visits, with one additional visit to the mound in the ninth inning if the defensive team has no visits left at the end of the eighth inning.
  • 3. Avoidance: The Field Timing Coordinator will now reset the clock after a dead ball when the pitcher has the ball and play is ready to resume.
  • 4. Batter faced requirement: A pitcher sent to warm up for an inning must face at least one batter.
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