Cubs vs Dodgers Odds kicked off the 2025 MLB regular season with two games in Tokyo, and the Dodgers won both. The Cubbies get a chance for payback starting Friday when they open a weekend series in Los Angeles. The Dodgers are favorites on the MLB odds. The Dodgers jumped on Cubs reliever Ben Brown in the fifth, scoring three runs, partly because of a throwing error by second baseman Jon Berti.